Application Note

Microsatellite Instability Assay For Response To Immunotherapy

Source: Q2 Solutions
Q2 Solutions

Available within our comprehensive immuno-oncology assay portfolio, Q2 Solutions’ MSI assay utilizes multiplex, fluorescent PCR and capillary electrophoresis to enable sensitive detection of five mononucleotide repeat markers (BAT-25, BAT-26, NR-21, NR-24 and MONO-27) in tumor FFPE specimens. Microsatellite instability at two or more mononucleotide loci is interpreted as MSI-High; microsatellite instability at a single mononucleotide locus is interpreted as MSI-Low; no instability at any of the loci tested is interpreted as microsatellite stable (MSS). The MSI assay has been analytically validated and is available for Research Use Only applications.

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