Shorter timelines, budget savings, easier data management—these are proven benefits of electronic data capture (EDC) for all phases of clinical research. Yet by continuing to use paper-based data capture, as of 2015, more than half of all new clinical trials were missing out on those benefits. That’s unfortunate – but what’s even more unfortunate is that the cost- and time-savings that researchers are missing could be used to increase the number and quality of clinical trials. And just imagine if those trials could focus on developing effective treatments that are urgently needed for diseases affecting millions of people worldwide. Applying EDC savings in that way would mean replacing paper could have not only business benefits, but public health implications as well.