By Craig Morgan, goBalto
Randomized clinical trials (RCT) remain the trusted standard for assessing pharmaceutical drug and medical device safety and efficacy. An RCT uses a carefully planned experimental framework to compare an intervention/treatment with a control, investigating the effect of each treatment option on a defined outcome. Patients participating in an RCT are carefully screened based on precise clinical criteria, and usually have very similar characteristics. Unfortunately, life does not always mirror the idealized world of an RCT.