Imagine its 2025. Participating in a clinical trial does not require travel to a clinical research facility or doctor’s office. Your mobile device (maybe a phone, watch, or even your glasses) is your link to the clinical research study and where you report general information and adverse events. Wearable sensors record data such as body temperature and blood glucose levels, which are sent automatically to the study electronic data capture (EDC) record. The study personnel visit you at home for drug administration and follow-up. When a visit is approaching, your mobile device provides automated reminders, allowing you to reschedule the appointment within a time frame permitted by the study protocol. And that’s just the beginning of what the future is likely to hold for so-called virtual clinical trials.