Application Notes & Case Studies

  1. Developing And Validating Clinical Receptor Occupancy Pharmacodynamic Biomarker Assays 9/25/2025

    Receptor occupancy (RO) assays assess drug-target engagement and support PK/PD modeling. Accurate RO requires customized assays using stabilized blood to monitor CD6 modulation in autoimmune therapy.

  2. Rapid Startup Phase 1 Cardiomyopathy CRISPR Gene Therapy 9/25/2025

    Hereditary transthyretin amyloidosis (ATTRv) is very rare, prompting a Phase 1 trial of in vivo CRISPR/Cas9 gene editing to reduce mutant protein and stop cardiomyopathy progression.

  3. Use Of Epiontis ID In A Phase 2 Psoriasis Trial 9/25/2025

    Mirikizumab’s Phase 2 trial explores IL-23 inhibition in psoriasis, measuring immune cell changes to assess its potential for long-term disease control and flare-up prevention.

  4. Redefining Accessibility For Pediatric Patients 9/24/2025

    Explore how meeting patients where they are can redefine what successful pediatric trial delivery looks like.

  5. Streamlining Global Respiratory Trial Complexities With Robust Data Capture Strategy 9/23/2025

    Want to see how eCOA solutions can simplify patient-reported data capture and accelerate global trials? Explore implementation strategies, lessons learned, and measurable results.

  6. Rescue Studies: Get Patient Recruitment Back On Track 9/22/2025

    What is a rescue study, and how can direct-to-patient digital recruitment be employed to rapidly boost recruitment and enrollment?

  7. Expand Bandwidth With A Trusted Regulatory Writing Partner 9/18/2025

    Find out how a mid-size biotech lacking the bandwidth, expertise, and resources to independently handle its regulatory writing requirements overcame this challenge.

  8. Duchenne Muscular Dystrophy Trial In China 9/17/2025

    A global sponsor conducting a Duchenne Muscular Dystrophy trial in China required reliable patient travel solutions to support children and families.

  9. Revitalizing Recruitment In A Lupus Rescue Study 9/11/2025

    Recruitment hurdles are overcome by leveraging engaged, data-sharing patient communities. See how a strategic, patient-centric approach delivered a pre-qualified clinical trial cohort quickly and efficiently.

  10. Preparing The Next Generation Of Clinical Research Professionals 9/4/2025

    Explore the live EDC platform that enabled Durham Tech to create a model for future-forward, hands-on education in clinical research.