Insights On Trial Design

  1. How To Reduce Screen Fail Rates 9/22/2025

    Explore the causes of high screen fail rates, their impact on patient recruitment for clinical trials, and how they disproportionately impact underrepresented demographics.

  2. Advancing Clinical Research In 2025: Meeting FDA Standards In DCT 1/22/2025

    Explore the key components of new FDA guidance on DCTs, including a focus on participant-centric designs and the use of Mobile Research Units (MRUs) to overcome geographic and technological barriers.

  3. How Early-Stage Planning Strategies Are Optimizing Drug Development 5/12/2025

    Early integration of a target product profile (TPP) into early-stage planning is pivotal for steering drug development toward both regulatory success and commercial impact.

  4. Triple-Negative Breast Cancer: Global Clinical Trial Landscape 1/30/2025

    With over 1,500 TNBC-focused clinical trials since 2019, research efforts into Triple-negative breast cancer (TNBC) treatments are accelerating despite challenges such as drug resistance.

  5. Bringing Clinical Trials To Everyone's Backyard 1/10/2025

    Learn how bringing clinical trials to any community around the world is not only possible but also increases patient access and reach and improves recruitment and retention.

  6. GSK And Medable Discuss The Next Phase Of DCTs 3/10/2025

    GSK and Medable share the value of embedding DCTs into strategic goals to enhance trial accessibility, diversity, and efficiency.

  7. Master Protocols: Implementing Effective Treatment Adaptations 8/25/2025

    From balancing treatment ratios and managing eligibility to accommodating site-specific readiness and protocol amendments, a well-designed IRT system enables seamless transitions.

  8. Accelerating IND-Enabling Studies With Automated Bioanalysis Workflows 9/2/2025

    Reimagined as automation-first, bioanalysis shifts from being an Investigational New Drug (IND) bottleneck to a catalyst for innovation—helping companies move therapies forward with greater confidence.

  9. Breaking Down Operational And Financial Complexity In Clinical Trials 12/8/2025

    Consider how factors like hybrid visits, enrollment patterns, and variable procedure volumes shape both the cadence and magnitude of site payments, supplier activity, and patient-related expenses.

  10. My First Forty Years At DIA 6/13/2024

    Following the simple logical flow we recommend for all Global Forum articles—What, So What, Now What—let’s delve into why DIA remains a cornerstone for professional growth and innovation in our field.