Obesity White Papers & Case Studies

  1. The Environmental Impact of Clinical Trials
    8/8/2013

    For many years it has been almost universally accepted that there are various sources that may impact or cause disease among which biological, social, and environmental differences have all been investigated. Many clinical trials have been conducted to assess the impact of the environment on outcomes e.g., the effect of the environment on the outcome of studies assessing the efficacy of drugs for patients with dry-eye syndrome, the impact of diet on obesity and cardiovascular disease, and the impact of the environment on autoimmune diseases have all been studied, as have many other interactions.

  2. Overcoming Clinical Challenges In Metabolic And Cardiovascular Disease With Metabolomics
    4/10/2013

    Metabolic diseases (e.g. obesity, type 2 diabetes, and hypertension) are a rapidly expanding health care concern. Although there is a high demand for novel therapies, the challenges are substantial as existing drugs typically fail due to lack of efficacy or safety, and clinical studies often extremely large and protracted. 

  3. Imaging For Cadiovascular Trials
    8/9/2012

    ICON Medical Imaging’s role as a medical imaging and endpoint core laboratory is to help sponsors assess the effect of therapies by independent and rigorous assessment of clinical and imaging endpoints.

  4. ICON Clinical Development Overview
    8/9/2012

    ICON is one of the world’s largest providers of outsourced development services to the pharmaceutical, biotechnology and medical device industries. We specialise in the strategic development, management and analysis of programs that support clinical development - from compound selection to Phase I-IV clinical studies.

  5. PK/PD Modeling & Simulation Datasheet
    2/13/2012
    ICON Development Solutions has industry-recognized expertise in the application and presentation of pharmacokinetic (PK) and pharmacodynamic (PD) principles critical for successful drug approval, with experience over the past 5 years that includes the following.
  6. Clinical Pharmacology Datasheet
    2/12/2012

    The clinical pharmacology team at ICON Development Solutions (ICON) has extensive experience in the design, study conduct and interpretation of clinical pharmacology studies across all major therapeutic areas.

  7. Clinical Pharmacodynamics Datasheet
    2/12/2012

    The main focus in Phase I clinical trials has traditionally been in assessment of safety and tolerability.