preclinical white papers and articles
-
No Shortcuts: Two Pathways To Building A Future For Huntington’s Disease Research
11/16/2021
One of the tenets of clinical research is that findings often result in more questions than answers. For Huntington’s disease, the journey toward understanding and treatment continues to be a methodical one. Dr. Ole Isacson highlights two pathways to ongoing research for this rare disease.
-
A Changing World In Gene Therapy Research: Exciting Opportunities For Medical Advancement And Biosafety Challenges
10/18/2021
In this report, key developments are highlighted in the field with a focus on biosafety and provides guidance for performing risk assessments on the currently approved gene therapy products as well as the most utilized types of investigational products in clinical trials.
-
Supporting Life Sciences From Startups To Commercialization
9/3/2021
Sikich’s SuiteSuccess for Life Sciences, built on NetSuite, helps companies grow from pre-revenue to commercialization in a fast, painless manner that ensures compliance and allows users to focus on what they do best: developing new medicines for patients who need them.
-
Physiological Functions Of The Amyloid Precursor Protein: A New Understanding
8/2/2021
Found in many tissues, the amyloid precursor protein, or APP, is most widely known for its role in Alzheimer’s disease. To find out more about this protein, read the available blog post.
-
13 New Alzheimer's Genes Identified In Genome Sequencing Study
8/2/2021
Recently, for the first time, researchers used a cutting-edge technique known as whole genome sequencing (WGS) to hunt for rare genomic variants associated with Alzheimer’s disease (AD), and they successfully identified 13 previously unknown Alzheimer’s genes. To find out more about these genes, read the available blog post.
-
Study Reveals How Humans Develop Larger Brains Than Other Apes
8/2/2021
Researchers at the Medical Research Council (MRC) Laboratory of Molecular Biology in Cambridge, United Kingdom, recently grew and studied miniature brain organoids to mimic the early brain development of humans, gorillas, and chimpanzees. Read the available blog post to find out more information.
-
Gene Expression In Some Fresh Brain Tissue Shown To Increase Activity After Death
8/2/2021
Recent research from the University of Illinois Chicago (UIC) reveals that some cells – brain cells, specifically – might even increase their activity after death and grow at an astonishing rate. To find out more about this research, read the available blog post.
-
Changes In Blood Vessels Shown Through Retinal Scans Could Indicate Early Stages Of Alzheimer's
8/2/2021
When you hear “retinal scan,” you might picture biometric security software – almost like something out of a James Bond film. However, a new study shows that retinal scans could serve as a means for understanding Alzheimer’s disease. To find out more, read the available blog.
-
Top Three Sources Of Evidence Suggesting Natural Killer Cells Role In Parkinson's Prevention
8/2/2021
According to the Global Burden of Disease study, 6.2 million patients live with Parkinson’s disease (PD) and this number is expected to double by 2040. To find out more, read the available blog post.
-
Human Immune System Beats HIV For The First Time
8/2/2021
The Centers for Disease Control and Prevention (CDC) describes human immunodeficiency virus (HIV) as a virus that attacks the body’s immune system. Without treatment, HIV can cause acquired immunodeficiency syndrome (AIDS). Read the available blog post to find out more.