ARTICLES BY JIM KREMIDAS

• What Sponsors Don't See: The Systems Behind Clinical Trial Delivery

  6/22/2026

  What do sponsors need from sites? Easy. How do they evaluate them? Not so easy (or accurate). In this column, Association Multisite Research Corporations (AMRC) Executive Director Jim Kremidas explains how sites and sponsors can make site evaluations better.

• Why Site Relationships With Sponsors and CROs Must Evolve Now

  11/24/2025

  Sites are central to drug development — we cannot run a trial without them — yet the industry continues to treat them as tactical, temporary instruments. It’s time to break this cycle, implores Jim Kremidas, executive director, Association of Multisite Research Corporations (AMRC).

• One And Done: How Bad Is The PI Turnover Problem?

  11/21/2018

  It’s ruefully referred to throughout the clinical trial industry as the “one and done” phenomenon, and it’s a problem that has plagued us for years. The term refers to physicians and other medical professionals who jump into a trial to assume the duties of principal investigators (PIs). Unfortunately, many are completely or relatively inexperienced in clinical trials; they’ve taken on the role of PI in hope of adding a new revenue stream to their practice or boosting their academic credentials.

• The Time Is Now To Professionalize The Clinical Trial Workforce

  8/30/2018

  Donna was the office manager for a trucking company. Terri worked at the reception desk of a contract research organization (CRO) straight out of high school. Tom lost his job teaching history at a community college after a round of layoffs. Jessica earned her living at a local hair salon.