Ecological momentary assessment (EMA) reveals how people experience hearing challenges beyond the clinic. Here, researchers highlight its relevance in designing real-world hearing studies.
- New Imaging Approach Could Improve IPF Trial Design
- Most Patients Learn About A Trial Online, But Is That What They Want?
- How Plain Language Summaries Created Under EU CTR Can Help Shape NIH Policy
- Long-Distance Rare Disease Trials: Why PLL Landed On Australia And New Zealand
- Is Moving From One-Off Solutions To A Technology Platform The Best Fit For Your R&D?
- How Digital Twins Are Reshaping Clinical R&D
- Why Are We Still Talking About Compensating Research Participants?
GUEST COLUMNISTS
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![two same digital person-GettyImages-964835390]( "How Digital Twins Are Reshaping Clinical R&D")
How Digital Twins Are Reshaping Clinical R&DDiscover how digital twins are helping predict outcomes, streamline recruitment, reduce patient burden, and accelerate clinical development.
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![hand holding credit card, laptop-GettyImages-2207149857]( "Why Are We Still Talking About Compensating Research Participants?")
Why Are We Still Talking About Compensating Research Participants?Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
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![Senior woman meeting with doctor-GettyImages-2205398466]( "Examining The Potential Of P-tau217 To Provide Earlier Diagnosis Of Alzheimer's")
Examining The Potential Of P-tau217 To Provide Earlier Diagnosis Of Alzheimer'sP-tau217 blood tests could accelerate Alzheimer’s diagnosis. Lilly’s Nino Sireci, MD, MSc, explains the research, evidence thus far, potential clinical use, and next steps.
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![stack of clipped documents-GettyImages-2213243327]( "The 50-Page Monitoring Report And The Illusion Of Control")
The 50-Page Monitoring Report And The Illusion Of ControlA massive decentralized trial showed why more monitoring doesn’t always mean more control — and how risk-based oversight can reveal what truly matters.
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![International Womans Day-GettyImages-2259815511]( "Autoimmune Drugs For Women: What To Bring To The Clinic")
Autoimmune Drugs For Women: What To Bring To The ClinicAutoimmune disease is one of the most sex-skewed categories in medicine. Sex, reproductive status, and hormonal state should not be treated as background noise.
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![site contract-gettyimages-2267854910]( "The Real Cost Of Sites Working Without An Enforceable Agreement: Why Your Site's Quality Of Earnings Is Suspect")
The Real Cost Of Sites Working Without An Enforceable Agreement: Why Your Site's Quality Of Earnings Is SuspectStarting site work before an enforceable agreement may look like flexibility, but it can drain leverage, create unrecoverable costs, and raise financial reporting and GCP concerns.
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![Lab Experiment-GettyImages-157697835]( "The U.S. Clinical Trial Recruiting Pipeline Report – August 2026")
The U.S. Clinical Trial Recruiting Pipeline Report – August 2026This WhichTrial report breaks down which drug trials are growing the most and the least, drugs that are no longer being studied, and new drugs to the clinic from July and August.
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![elderly care, rehabilitation, recovery-GettyImages-2274991410]( "How VNS-REHAB Aims To Improve Stroke Recovery After Patients Have Plateaued")
How VNS-REHAB Aims To Improve Stroke Recovery After Patients Have PlateauedLearn how a stroke trial standardized intensive therapy, sustained patient adherence, and exposed access barriers after FDA approval.
CLINICAL TRIAL WHITE PAPERS
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![Data analysis science and big data with AI technology-GettyImages-1979289147]( "Trust In AI Agents Has To Be Earned Continuously, Not Just Once")
Trust In AI Agents Has To Be Earned Continuously, Not Just OnceThis white paper lays out how ongoing performance monitoring, version control, and audit-ready traceability keep agentic AI trustworthy in a regulated environment.
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Deriving Reliable Clinical Outcome Scores From Continuous DHT Data6/10/2025
DHT-derived endpoints, especially percentile-based metrics, hold promise for robust, scalable measurement in clinical trials—provided they're chosen statistically and with adherence in mind.
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A Promising Rebound in Clinical Trials10/23/2024
This report explores how clinical trials bounced back in 2023 from their decline a year earlier despite continued geopolitical, regulatory, and pricing pressures.
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How Digitized Protocols Are Accelerating Clinical Research4/15/2025
Digitized protocols, enhanced by artificial intelligence (AI), are transforming clinical trial operations by accelerating document generation, system integration, and trial optimization.
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State Of Clinical Trial Technology: The AI Inflection Point2/12/2026
Digital maturity gaps are widening in clinical research. Connected workflows speed insights and execution, while manual processes leave organizations increasingly behind.
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Elevating Patient Centricity In Clinical Trials2/17/2025
How can the integration of patient perspectives throughout the clinical trial process enhance engagement and outcomes?
CLINICAL TRIAL APP NOTES & CASE STUDIES
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GSK And Medable Discuss The Next Phase Of DCTs3/10/2025
GSK and Medable share the value of embedding DCTs into strategic goals to enhance trial accessibility, diversity, and efficiency.
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Continuity And Risk Mitigation Following Unexpected QPPV Resignation5/26/2026
Rapid escalation and clear interim governance ensured compliance and operational continuity following an unexpected QPPV resignation, reducing inspection risk during a critical pharmacovigilance transition.
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FDA Approvals Of Two Novel Agents For The Acute Treatment Of Migraine7/31/2026
Parallel trials, compressed timelines, thousands of patients. Discover the data oversight strategies that kept two programs on track to approval
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Supporting Seamless Execution Across Early Phase Alzheimer's Trials7/31/2026
Enrollment hesitancy, staff turnover, and compressed timelines threatened a multi-phase Alzheimer's program. Learn the operational approach that delivered results at every stage.
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From Months To Hours: MMC Medical's EDC Revolution3/31/2026
Learn how a specialized CRO reduced study build times by 95%. Discover strategies for template reusability and flexible resource scaling to accelerate early-stage medical device validation.
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Partnership Driving Superior Enrollment And Speed In Phase III Trial1/31/2025
Examine the partnership between CRIO and Sitero, including how it underscores the significant impact of technology in optimizing trial performance and accelerating treatment development.
NEWSLETTER ARCHIVE
- 10.05.26 -- Why Are We Still Talking About Compensating Research Participants?
- 10.02.26 -- Sponsors Are Automating Trials With AI — But Can They Trust The Output?
- 10.01.26 -- Health Policy Is Shifting Fast — Is Your Compliance Strategy Keeping Pace?
- 10.01.26 -- Better Site Support Starts Early
- 09.30.26 -- Old Trial Playbooks Are Breaking Under New Complexity
RECRUITMENT AND DIVERSITY
This section includes some helpful resources regarding patient recruitment and diversity in clinical trials, including this link to the FDA's guidance on diversity action plans.
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![Mature student Studying-GettyImages-1460342076]( "Most Patients Learn About A Trial Online, But Is That What They Want?")
Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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![hand holding credit card, laptop-GettyImages-2207149857]( "Why Are We Still Talking About Compensating Research Participants?")
Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
-
![International Womans Day-GettyImages-2259815511]( "Autoimmune Drugs For Women: What To Bring To The Clinic")
Autoimmune disease is one of the most sex-skewed categories in medicine. Sex, reproductive status, and hormonal state should not be treated as background noise.
FOCUS ON PATIENTS
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![Mature student Studying-GettyImages-1460342076]( "Most Patients Learn About A Trial Online, But Is That What They Want?")
Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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![Healthcare, Medical service, Health insurance-GettyImages-2191629470]( "How Plain Language Summaries Created Under EU CTR Can Help Shape NIH Policy")
As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.
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![hand holding credit card, laptop-GettyImages-2207149857]( "Why Are We Still Talking About Compensating Research Participants?")
Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
