Learn how to evaluate medical LLMs for clinical trials by weighing readiness, risk, validation, integration, hidden costs, and supplier controls.
- 5 Sponsor Contracting Issues That Delay Clinical Trials — And How To Avoid Them
- Participant Payment — Make It Make Cents
- What Ecological Momentary Assessment Taught Us About Real-World Hearing Outcomes
- Calidi's Study Aims To Have An Oncolytic Virus Outsmart The Immune System
- New Imaging Approach Could Improve IPF Trial Design
- With CROs, Decide What You Can Actually Manage
- How Plain Language Summaries Created Under EU CTR Can Help Shape NIH Policy
GUEST COLUMNISTS
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Most Patients Learn About A Trial Online, But Is That What They Want?
Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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How Plain Language Summaries Created Under EU CTR Can Help Shape NIH Policy
As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.
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Long-Distance Rare Disease Trials: Why PLL Landed On Australia And New Zealand
Australia and New Zealand had a lot to offer PLL Therapeutics, but speed and savings aren't the only upsides for running its rare disease trial from its European home.
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Is Moving From One-Off Solutions To A Technology Platform The Best Fit For Your R&D?
Integrated technology platforms can connect R&D data, accelerate trials, strengthen quality, and cut costs — but successful adoption requires more than AI.
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How Digital Twins Are Reshaping Clinical R&D
Discover how digital twins are helping predict outcomes, streamline recruitment, reduce patient burden, and accelerate clinical development.
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Why Are We Still Talking About Compensating Research Participants?
Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
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Examining The Potential Of P-tau217 To Provide Earlier Diagnosis Of Alzheimer's
P-tau217 blood tests could accelerate Alzheimer’s diagnosis. Lilly’s Nino Sireci, MD, MSc, explains the research, evidence thus far, potential clinical use, and next steps.
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The 50-Page Monitoring Report And The Illusion Of Control
A massive decentralized trial showed why more monitoring doesn’t always mean more control — and how risk-based oversight can reveal what truly matters.
CLINICAL TRIAL WHITE PAPERS
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Real-World Value Realized From DHTs In Clinical Trials
Explore four real-world examples of clinical trials that successfully integrated DHTs. Each case study highlights how DHTs impacted specific aspects of trial design.
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Hospital-Based eCOA Implementation: Real Challenges In Infectious Disease Trials11/21/2025
This resource outlines proven strategies to reduce delays, improve compliance, and meet regulatory standards for PRO data in infectious disease studies.
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State of Materiovigilance: Gaps, Technology & Outsourcing5/12/2026
Explore how pharma and biotech companies are using AI, outsourcing, and new technologies to strengthen materiovigilance for complex drug-device products.
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Optimizing Site Activation To Accelerate Clinical Trials6/5/2025
Clinical trial site activation delays are a major bottleneck in drug development, hampering trial timelines and funding flows. To reverse this trend, site-focused solutions are being prioritized.
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Navigating Adverse Immunostimulation: A Practical Guide For Clinical Researchers9/30/2025
Explore a systematic approach to evaluate adverse immunostimulation (AIS) in drug development through standardized biomarker sampling and tailored management strategies.
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What Re-Acquisition In Retinal Imaging Is Really Costing Your Program4/6/2026
High screen failure rates and patient dropout often stem from preventable imaging errors. Learn how proactive quality control and patient-centric logistics secure critical retinal trial data.
CLINICAL TRIAL APP NOTES & CASE STUDIES
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Digital Outcome Measures Approved As Primary Endpoint In Cardiopulmonary Study4/15/2025
Discover how a clinical development program was saved using objective, continuous digital outcome measures.
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How A Biotech Startup Transformed Its Clinical Trial Supply Management2/25/2026
Don’t let your trial get lost in the shuffle of legacy vendors. See how a high-touch, consultative approach can protect your study’s future.
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Reducing The Burden Of Patient Retention And Improving Continuity1/6/2026
Immunology trials often place a sustained burden on participants. However, integrating Home Trial Support (HTS) into a Phase 3 immunology trial can help improve the overall study experience.
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Advancing Dose Escalation Strategies With Bayesian Modeling8/12/2025
A CRO was engaged to help a biotechnology sponsor develop a novel oncology therapy design and execute a multicenter, open-label Phase 1/2 dose escalation and expansion study in advanced solid tumors.
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Accelerating CRO Study Deployment At Scale7/7/2025
A top-3 CRO and a top-10 pharmaceutical company partnered with Medable to help accelerate, scale, and standardize their eCOA trials. See how they accomplished it.
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Rescuing A Global Full-Service Phase III Trial For A Late-Stage Oncology Biotech10/2/2025
This case underscores the expertise employed in a comprehensive strategy and set of services that were used to salvage a Phase III clinical trial for ovarian cancer and ensure its timely completion.
NEWSLETTER ARCHIVE
- 10.09.26 -- Expertise That Scales: Trial Operations, Safety Signals, And HEOR Skills
- 10.09.26 -- From eConsent To Central eSource: Tools To Speed Startup And Lighten Site Work
- 10.08.26 -- Regulatory Readiness From Phase I Onward
- 10.07.26 -- Investigator Responsibilities In Decentralized Clinical Trials
- 10.07.26 -- Where RWE Is Still More Hype Than Reality
RECRUITMENT AND DIVERSITY
This section includes some helpful resources regarding patient recruitment and diversity in clinical trials, including this link to the FDA's guidance on diversity action plans.
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Participant payment practices and expectations vary wildly. With advocate T.J. Sharpe, explore why sponsors need to rethink how they appreciate participants' time, effort, and burden.
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Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
FOCUS ON PATIENTS
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Participant payment practices and expectations vary wildly. With advocate T.J. Sharpe, explore why sponsors need to rethink how they appreciate participants' time, effort, and burden.
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Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.