Learn how to evaluate medical LLMs for clinical trials by weighing readiness, risk, validation, integration, hidden costs, and supplier controls.
- 5 Sponsor Contracting Issues That Delay Clinical Trials — And How To Avoid Them
- Participant Payment — Make It Make Cents
- What Ecological Momentary Assessment Taught Us About Real-World Hearing Outcomes
- Calidi's Study Aims To Have An Oncolytic Virus Outsmart The Immune System
- With CROs, Decide What You Can Actually Manage
- New Imaging Approach Could Improve IPF Trial Design
- Most Patients Learn About A Trial Online, But Is That What They Want?
GUEST COLUMNISTS
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Most Patients Learn About A Trial Online, But Is That What They Want?
Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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How Plain Language Summaries Created Under EU CTR Can Help Shape NIH Policy
As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.
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Long-Distance Rare Disease Trials: Why PLL Landed On Australia And New Zealand
Australia and New Zealand had a lot to offer PLL Therapeutics, but speed and savings aren't the only upsides for running its rare disease trial from its European home.
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Is Moving From One-Off Solutions To A Technology Platform The Best Fit For Your R&D?
Integrated technology platforms can connect R&D data, accelerate trials, strengthen quality, and cut costs — but successful adoption requires more than AI.
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How Digital Twins Are Reshaping Clinical R&D
Discover how digital twins are helping predict outcomes, streamline recruitment, reduce patient burden, and accelerate clinical development.
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Why Are We Still Talking About Compensating Research Participants?
Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
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Examining The Potential Of P-tau217 To Provide Earlier Diagnosis Of Alzheimer's
P-tau217 blood tests could accelerate Alzheimer’s diagnosis. Lilly’s Nino Sireci, MD, MSc, explains the research, evidence thus far, potential clinical use, and next steps.
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The 50-Page Monitoring Report And The Illusion Of Control
A massive decentralized trial showed why more monitoring doesn’t always mean more control — and how risk-based oversight can reveal what truly matters.
CLINICAL TRIAL WHITE PAPERS
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The Evolving Landscape Of Emerging Biopharma: Modern Trends And Flexible Trial Designs
Running complex trials on a lean budget? See how adaptive designs, decentralized models, and early real-world evidence help emerging drug developers plan globally and get therapies to patients faster.
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Merits Of A Multifaceted Approach To Clinical Trial Recruitment1/27/2025
The best way to address clinical trial recruitment challenges is with a multifaceted approach that goes beyond traditional channels and ways of thinking.
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Clinical Trial Starts Rose At Slower Pace In 202412/8/2025
Clinical trial starts grew 5.5% to 10,503 in 2024, a slowdown from 2023’s 9.4% rise in trial starts. Sustained geopolitical and global regulatory pressures on pharma contributed to curbing momentum.
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Open-Label Study Assessing Relative And Absolute Bioavailability1/26/2026
Consistent absorption across different formulations and dietary conditions ensures stable therapeutic exposure. This flexibility simplifies patient dosing schedules and supports manufacturing transitions.
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eSource Purpose Is Not Just To Complete The EDC7/7/2025
Central eSource transforms data capture from a passive, back-end chore into an active, real-time quality and compliance engine—delivering benefits that extend beyond faster EDC feeds and reduced SDV.
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The Rapid Digitization Of Trials11/7/2024
It’s no secret that more trials are going digital. Hear from a panel of industry experts including Sanofi, Bayer, and the Clinical Trials Transformation Initiative (CTTI) as they discuss the evolution of digital trials and share their experiences.
CLINICAL TRIAL APP NOTES & CASE STUDIES
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Rescuing A Global Full-Service Phase III Trial For A Late-Stage Oncology Biotech10/2/2025
This case underscores the expertise employed in a comprehensive strategy and set of services that were used to salvage a Phase III clinical trial for ovarian cancer and ensure its timely completion.
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Increasing Participation In World-Class Cancer Research In Northwest Arkansas3/26/2026
Discover how data automation and integrated screening help community cancer centers offer clinical research as a standard care option, ensuring all patients have access to the latest treatments.
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Supporting Seamless Execution Across Early Phase Alzheimer's Trials7/31/2026
Enrollment hesitancy, staff turnover, and compressed timelines threatened a multi-phase Alzheimer's program. Learn the operational approach that delivered results at every stage.
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Optimizing EDC Strategy And Data Collection for a Rare Disease Trial6/11/2025
Explore how Veristat created a forward-looking roadmap for EDC and CRFs integration for a small biotech sponsor, ensuring a future-ready data ecosystem without overcomplicating current operations.
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Digital Outcome Measures Approved As Primary Endpoint In Cardiopulmonary Study4/15/2025
Discover how a clinical development program was saved using objective, continuous digital outcome measures.
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Trial Rescue And Reconnaissance4/15/2026
Explore a strategic partnership that resulted in a rescue plan for a Phase III oncology trial that was facing high site decline rates.
NEWSLETTER ARCHIVE
- 10.10.26 -- Best Of September
- 10.09.26 -- Expertise That Scales: Trial Operations, Safety Signals, And HEOR Skills
- 10.09.26 -- From eConsent To Central eSource: Tools To Speed Startup And Lighten Site Work
- 10.08.26 -- Regulatory Readiness From Phase I Onward
- 10.07.26 -- Investigator Responsibilities In Decentralized Clinical Trials
RECRUITMENT AND DIVERSITY
This section includes some helpful resources regarding patient recruitment and diversity in clinical trials, including this link to the FDA's guidance on diversity action plans.
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Participant payment practices and expectations vary wildly. With advocate T.J. Sharpe, explore why sponsors need to rethink how they appreciate participants' time, effort, and burden.
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Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
FOCUS ON PATIENTS
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Participant payment practices and expectations vary wildly. With advocate T.J. Sharpe, explore why sponsors need to rethink how they appreciate participants' time, effort, and burden.
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Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.