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Synaptic Regeneration And The Future Of Alzheimer's R&D

For too long, treating Alzheimer’s disease has been a case of “managed decline.” We need to move beyond slowing disease progression toward achieving tangible functional recovery.

GUEST COLUMNISTS

Contracting For AI In Clinical Trials: Cybersecurity, Monitoring, And Risk Allocation (Part 3)
Leibowitz Law shares the third installment of its three-part series on contracting for AI in clinical trial operations. Part 3 picks up with cybersecurity, monitoring and validation, and risk allocation.
Contracting For AI In Clinical Trials: Data Rights And Regulatory Compliance (Part 2)
Leibowitz Law's three-part series examines how AI is being used in clinical trial operations and the contractual and operational risks that follow. Part 2 demonstrates why organizations must understand where it is used, how it interacts with data, and where the risks lie.
Where AI Appears In Clinical Trials — And Why Contracts Need To Catch Up (Part 1)
Leibowitz Law's three-part series examines how AI is being used in clinical trial operations and the contractual and operational risks that follow. Part 1 outlines where AI appears in ClinOps and supporting technologies, and the questions companies and organizations should ask when AI touches data.
Designing Trials Patients Can Actually Complete: Lessons From The SWIFT Deep TMS Study
Being time conscious and attuned to patient needs are two contributing factors to trials that recruit and retain patients for the duration.
It's A Fact: Sharing Clinical Trial Results With Participants Builds Trust
CISCRP experts share results from their annual Perceptions & Insights Study showing that patients continue to place a high value on receiving both individual and overall study results.
When AI Agents Start Researching Trials On Behalf Of Patients, What Happens?
Right now, patients are using AI agents to find clinical trials. But soon enough, these AI tools will be doing it on their own and feeding patients the results. Recruitment expert Ross Jackson discusses this shift and what it will mean for sponsors.
The U.S. Clinical Trial Recruiting Pipeline Report – May 2026
This WhichTrial report breaks down which drug trials are growing the most and the least, drugs that are no longer being studied, and new drugs to the clinic from March 7 to May 1, 2026.
Safe And Scalable AI Deployment For Clinical Trials
When life sciences organizations lack a structured, evidence-based methodology for scaling AI tools safely and effectively, they put clinical development at risk. Partha Anbil and Partha Khot team up to share a practical approach to its implementation.

CLINICAL TRIAL WHITE PAPERS

Challenges And New Approaches To Developing Clinical Evidence For Medical Devices
Learn about the challenges and new approaches to developing clinical evidence for medical devices, including decentralized trials, adaptive studies, in silico trials, and real-world evidence.

Optimizing Site Activation To Accelerate Clinical Trials
6/5/2025

Clinical trial site activation delays are a major bottleneck in drug development, hampering trial timelines and funding flows. To reverse this trend, site-focused solutions are being prioritized.
The Impact Of High Inflation And The Great Resignation On Clinical Site Budgeting
10/30/2024

The twin pressures of inflation and attrition prolong negotiations between sponsors and clinical sites, stalling drug development. Sponsors need up-to-date, reliable benchmark data to negotiate fair market value budgets.
Unique IRT Implementation Considerations For Personalized Medicine Trials
8/22/2025

The rise of personalized and precision medicine is reshaping the clinical trial landscape and, as the number of these specialized trials increases, so does the complexity of managing them effectively.
Challenges, Opportunities For Recruitment In The Digital Age
10/20/2025

Health literacy gaps and online misinformation hinder clinical trial recruitment. Meeting patients where they are — digitally and educationally — can improve engagement and enrollment success.
What the FDA Looks For In Global Development Programs Today
1/16/2026

Mastering the complexities of multi-regional clinical trials requires aligning global data with evolving regulatory expectations to ensure treatment consistency and successful drug approval.

More Clinical Trial White Papers

CLINICAL TRIAL APP NOTES & CASE STUDIES

Enhance Access And Improve Retention In Rare Disease Trials With HTS
4/17/2025

Home Trial Support (HTS) provides a solution to improving participant recruitment and retention during musculoskeletal studies.
Building A High-Quality IND From Scratch With Strategic Gap Analysis
8/12/2025

A biotech sponsor lacking in-house regulatory expertise engaged a partner to obtain strategic regulatory review, medical writing, project management, and electronic publishing (eCTD).
Transforming Clinical Trial Sites With Research Study Rockstar
2/10/2025

This innovative platform streamlines workflows, automates patient communication, and provides intuitive dashboards to address prevalent pain points faced by trial coordinators.
Use Case: A Patient-Centric Approach To Site Selection
1/27/2025

Discover how Citeline’s robust datasets, combined with real-world data, inform intelligent site and investigator selection for a rare, autoimmune disease.
How Cara Therapeutics Increased Compliance And Reduced Study Team Burden
7/31/2025

Delve into the partnership that helped Cara Therapeutics achieve a significant milestone in their clinical research efforts to transform the lives of chronic pruritus patients.
Participant Support In Oncology Trials With Cachexia-Related Burden
4/21/2026

Coordinated travel, reimbursements, and visit logistics for oncology participants experiencing fatigue, weight loss, and reduced mobility, helping reduce dropouts and keep people engaged.

More Clinical Trial App Notes & Case Studies

NEWSLETTER ARCHIVE

More Newsletters

RECRUITMENT AND DIVERSITY

This section includes some helpful resources regarding patient recruitment and diversity in clinical trials, including this link to the FDA's guidance on diversity action plans.

How Did You End Up In Clinical Research?

To commemorate Clinical Trials Day, we asked clinical researchers to share their story, answering, "How did you get into clinical research?"
When AI Agents Start Researching Trials On Behalf Of Patients, What Happens?

Right now, patients are using AI agents to find clinical trials. But soon enough, these AI tools will be doing it on their own and feeding patients the results. Recruitment expert Ross Jackson discusses this shift and what it will mean for sponsors.
The U.S. Clinical Trial Recruiting Pipeline Report – May 2026

This WhichTrial report breaks down which drug trials are growing the most and the least, drugs that are no longer being studied, and new drugs to the clinic from March 7 to May 1, 2026.

FOCUS ON PATIENTS

Designing Trials Patients Can Actually Complete: Lessons From The SWIFT Deep TMS Study

Being time conscious and attuned to patient needs are two contributing factors to trials that recruit and retain patients for the duration.
It's A Fact: Sharing Clinical Trial Results With Participants Builds Trust

CISCRP experts share results from their annual Perceptions & Insights Study showing that patients continue to place a high value on receiving both individual and overall study results.
Precision Medicine Needs Better Infrastructure — And We Already Have The Models For It

Standard methods for evaluating clinical trial representativeness perform poorly when the trial population differs from the broader disease population in a patient registry. June Cha, Ph.D., MPH, explains how the right metrics can make a difference.