Learn how to evaluate medical LLMs for clinical trials by weighing readiness, risk, validation, integration, hidden costs, and supplier controls.
- 5 Sponsor Contracting Issues That Delay Clinical Trials — And How To Avoid Them
- Participant Payment — Make It Make Cents
- What Ecological Momentary Assessment Taught Us About Real-World Hearing Outcomes
- Calidi's Study Aims To Have An Oncolytic Virus Outsmart The Immune System
- With CROs, Decide What You Can Actually Manage
- New Imaging Approach Could Improve IPF Trial Design
- Most Patients Learn About A Trial Online, But Is That What They Want?
GUEST COLUMNISTS
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Most Patients Learn About A Trial Online, But Is That What They Want?
Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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How Plain Language Summaries Created Under EU CTR Can Help Shape NIH Policy
As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.
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Long-Distance Rare Disease Trials: Why PLL Landed On Australia And New Zealand
Australia and New Zealand had a lot to offer PLL Therapeutics, but speed and savings aren't the only upsides for running its rare disease trial from its European home.
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Is Moving From One-Off Solutions To A Technology Platform The Best Fit For Your R&D?
Integrated technology platforms can connect R&D data, accelerate trials, strengthen quality, and cut costs — but successful adoption requires more than AI.
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How Digital Twins Are Reshaping Clinical R&D
Discover how digital twins are helping predict outcomes, streamline recruitment, reduce patient burden, and accelerate clinical development.
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Why Are We Still Talking About Compensating Research Participants?
Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
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Examining The Potential Of P-tau217 To Provide Earlier Diagnosis Of Alzheimer's
P-tau217 blood tests could accelerate Alzheimer’s diagnosis. Lilly’s Nino Sireci, MD, MSc, explains the research, evidence thus far, potential clinical use, and next steps.
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The 50-Page Monitoring Report And The Illusion Of Control
A massive decentralized trial showed why more monitoring doesn’t always mean more control — and how risk-based oversight can reveal what truly matters.
CLINICAL TRIAL WHITE PAPERS
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Navigating The Challenges Of Large, International Phase III Breast Cancer Trials
In the competitive landscape of breast cancer research, aligning biomarker testing, regulatory pathways, and regional operations from day one creates a path to faster enrollment and stronger outcomes.
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Rethinking Trial Access Through Trust-Driven Design And Local Collaboration5/19/2026
Locally embedded research models help sponsors reach underserved populations while reducing burden on patients and health systems alike.
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AI in Pharma: Benefits, Risks, And The Road Ahead10/23/2024
How could leveraging AI technologies, including machine learning (ML) and generative AI (GenAI), enable your company to streamline processes from drug discovery to post-launch?
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Five Preventable Clinical Design Pitfalls And How To Avoid Them7/21/2026
While late-stage trial attrition is often attributed to inadequate safety or efficacy, the true failure may be insufficient upstream planning and/or misalignment between clinical and commercial goals.
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Collaborate To Improve The Patient Experience8/8/2026
Fragmented trial operations trigger costly enrollment delays. Discover how operational alignment among sponsors, CROs, and site networks drives patient retention and study success.
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Flying On Two Wings: Balancing Local Agility And Global Quality In China8/12/2026
As China expands its role in drug development, injectable therapy programs face new demands. Learn how manufacturers are scaling quality, devices, and production for global success.
CLINICAL TRIAL APP NOTES & CASE STUDIES
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Partnership Driving Superior Enrollment And Speed In Phase III Trial1/31/2025
Examine the partnership between CRIO and Sitero, including how it underscores the significant impact of technology in optimizing trial performance and accelerating treatment development.
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Automated Trial Monitoring Workflows Make A Lean Team More Efficient1/7/2026
A pharmaceutical therapy developer was looking to automate reports, confirmation letters, and follow-up letters. See what happened when they adopted a cloud-based solution for end-to-end trial management.
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End-To-End Clinical, Biometrics, And Regulatory Support In Neurology6/4/2026
Discover how an integrated NDA strategy aligned data, vendors, and regulatory execution to achieve an on-time submission and approval without major FDA queries.
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Streamlining Phase 1 Trials With The Mobile Vision Pod1/29/2025
A contract research organization formed a partnership to address significant challenges during a Phase 1 clinical trial for a corneal disease treatment through the use of a Mobile Vision Pod.
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Reinventing Prostate Cancer Diagnostics With An All-In-One Platform3/31/2026
Discover how a lean research team saved an estimated $100k and reached 95% data compliance by unifying their clinical workflow.
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No More Swiss Holes: Filling The Gaps In Clinical Trial Disclosure1/14/2026
This use case shows how sponsors can gain clarity on disclosure requirements when entering a new country.
NEWSLETTER ARCHIVE
- 10.10.26 -- Best Of September
- 10.09.26 -- Expertise That Scales: Trial Operations, Safety Signals, And HEOR Skills
- 10.09.26 -- From eConsent To Central eSource: Tools To Speed Startup And Lighten Site Work
- 10.08.26 -- Regulatory Readiness From Phase I Onward
- 10.07.26 -- Investigator Responsibilities In Decentralized Clinical Trials
RECRUITMENT AND DIVERSITY
This section includes some helpful resources regarding patient recruitment and diversity in clinical trials, including this link to the FDA's guidance on diversity action plans.
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Participant payment practices and expectations vary wildly. With advocate T.J. Sharpe, explore why sponsors need to rethink how they appreciate participants' time, effort, and burden.
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Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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Should we be compensating research participants? And is that even a question worth asking? Lindsay McNair, MD, and Ken Getz say yes despite recent data that doesn't point to a clear ROI.
FOCUS ON PATIENTS
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Participant payment practices and expectations vary wildly. With advocate T.J. Sharpe, explore why sponsors need to rethink how they appreciate participants' time, effort, and burden.
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Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
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As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.