Teams want AI systems that can answer complex scientific questions across value chain, but as these systems move closer to production, a recurring problem is becoming visible.
- Testing Early Treatment In Head And Neck Cancer Without Compromising Curative Care
- Founders, Fortitude, And Clinical Trials
- The New Clinical Trial Regulatory Landscape Balances Speed, Quality, and Compliance — Are You Ready?
- Get Ready For Regulators With This Speed-Quality-Compliance Framework
- Can Psychedelic‑Assisted Treatment Redefine Emotional Care In Oncology?
- The U.S. Clinical Trial Recruiting Pipeline – September 2026
- Unlocking AI Value For Clinical Research Associates
GUEST COLUMNISTS
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The U.S. Clinical Trial Recruiting Pipeline – September 2026
This WhichTrial report breaks down which drug trials are growing the most and the least, drugs that are no longer being studied, and new drugs to the clinic from August to Septemeber.
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Unlocking AI Value For Clinical Research Associates
Clinical research associates (CRAs) have largely been late to adopt AI. CRAs who adopt it can streamline repetitive work while also freeing capacity for high-judgment work.
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Your EDC Query Count Is Trying To Tell You Something
A rising EDC query count may reveal more than dirty data. Learn how query patterns can expose upstream problems in trial workflows, training, and CRF design.
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Can A Universal Health Screening Help Stop Clinical Trial Dropouts?
Could comprehensive health scans give trial participants meaningful value — and help sponsors reduce costly dropouts?
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Can Your Team Coordinate The CRO Model You've Chosen?
Choosing the right CRO model matters less than a sponsor’s ability to coordinate it. Here’s how to match outsourcing strategy to internal capacity.
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To Pick The Right Medical LLM, First Assess Your Readiness
Learn how to evaluate medical LLMs for clinical trials by weighing readiness, risk, validation, integration, hidden costs, and supplier controls.
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Your Company Needs Compliance Expertise — But When And From Whom?
When should a biotech formalize compliance? Learn how risk, funding, clinical activity, and commercialization shape the right expertise and structure.
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5 Sponsor Contracting Issues That Delay Clinical Trials — And How To Avoid Them
CTA negotiations don’t have to stall study start-up. Learn five sponsor-side contracting issues that cause delays and practical ways to prevent them.
CLINICAL TRIAL WHITE PAPERS
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Beyond A Single Disease: Traversing Complexity In Breast Cancer Clinical Development
Biomarkers, new therapies, and tough enrollment hurdles are reshaping breast cancer trials. Get the insights to plan smarter.
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2026 State Of Clinical Trial Technology: The Five Strategic Imperatives3/12/2026
AI acceleration and digital fragmentation are reshaping clinical trials. Discover five imperatives driving interoperability, smarter site enablement, and data‑ready workflows for future‑ready operations.
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4 New Approvals In Q3 Across Gene, Cell, RNA Therapies11/13/2025
Q3 2025 brought notable progress across the gene, cell, and RNA therapy landscape, marked by four new global approvals. While regulatory progress continued, clinical development activity slowed.
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Writing An IND Module 3 For Cell And Gene Therapy Products9/1/2025
This whitepaper outlines the critical considerations for CGT Investigational New Drug (IND) Module 3, as well as how to avoid clinical holds and ensure regulatory readiness.
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State of Materiovigilance: Gaps, Technology & Outsourcing5/12/2026
Explore how pharma and biotech companies are using AI, outsourcing, and new technologies to strengthen materiovigilance for complex drug-device products.
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Navigating Project Optimus And The Rapidly Changing Oncology Development Landscape9/1/2025
Project Optimus and adaptive trial designs are reshaping oncology development, improving patient outcomes, and streamlining approval pathways.
CLINICAL TRIAL APP NOTES & CASE STUDIES
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How a Biopharmaceutical Company Improved Site Satisfaction8/12/2026
Eliminate site payment delays and reduce clinical trial admin burden. Learn how one sponsor cut payment timelines from 120+ days to under 30 days while boosting site satisfaction.
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Advancing IHC Assays From RUO To Clinical Trials And CDx8/21/2026
Examine how an exploratory IHC assay evolved into a multi-indication clinical program through integrated assay development, validation, regulatory strategy, and scientific collaboration.
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Streamlining Pediatric Clinical Trials With Vestigo®5/8/2026
Utilizing a centralized, automated platform can eliminate the friction of manual accountability logs, ensuring audit readiness while providing real-time visibility into financial reporting.
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Reserving Data Integrity With Retrospective Manual Entry7/5/2026
A look at implementing randomization mid-trial by reconstructing subject and inventory records without disrupting sites or compromising data integrity.
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Overcoming Unexpected Obstacles In A Phase 1 Study1/29/2025
Discover how the implementation of mobile vision clinics (MVCs) was used to enhance efficiency in a Phase 1 clinical trial.
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Optimizing Wearable Adherence In A Phase 3 Oncology Trial5/15/2026
Long-term wearable monitoring only works if patients keep wearing the device, and in oncology trials, that’s easier said than done.
NEWSLETTER ARCHIVE
- 10.21.26 -- Choose Your Approach: Traditional, Hybrid Or Decentralized
- 10.21.26 -- From Protocol Design To Site Workflows: Building Trials That Run Smarter
- 10.20.26 -- Smarter Trial Tech: Vetting Medical LLMs, Rethinking eCOA, And Aligning eDiary Design
- 10.19.26 -- Autoimmune Drugs For Women: What To Bring To The Clinic
- 10.16.26 -- Turning Data Into Decisions: Smarter Tools For Faster, Stronger Trials
RECRUITMENT AND DIVERSITY
This section includes some helpful resources regarding patient recruitment and diversity in clinical trials, including this link to the FDA's guidance on diversity action plans.
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Could comprehensive health scans give trial participants meaningful value — and help sponsors reduce costly dropouts?
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Participant payment practices and expectations vary wildly. With advocate T.J. Sharpe, explore why sponsors need to rethink how they appreciate participants' time, effort, and burden.
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Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.
FOCUS ON PATIENTS
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Can early APG-157 treatment control head and neck cancer without delaying curative care? A Phase 3 trial puts timing, safety, and outcomes to the test.
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Psychedelic-assisted treatment may offer faster, lasting relief for cancer patients facing adjustment disorder, depression, and anxiety.
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Could comprehensive health scans give trial participants meaningful value — and help sponsors reduce costly dropouts?