GUEST COLUMNISTS

• What Ecological Momentary Assessment Taught Us About Real-World Hearing Outcomes

  Ecological momentary assessment (EMA) reveals how people experience hearing challenges beyond the clinic. Here, researchers highlight its relevance in designing real-world hearing studies.

• Calidi's Study Aims To Have An Oncolytic Virus Outsmart The Immune System

  Calidi’s Eric Poma, Ph.D., explains how CLD-401 could evade immune clearance — and how the biotech is designing Phase 1 to prove safety and efficacy fast.

• New Imaging Approach Could Improve IPF Trial Design

  AI-powered quantitative CT could help sponsors detect treatment effects earlier, strengthen IPF trial endpoints, and make better go/no-go decisions.

• Most Patients Learn About A Trial Online, But Is That What They Want?

  Patients want to hear about clinical trials from their doctors — but most learn out online. CISCRP explores how industry can change the referral pathway for better.

• How Plain Language Summaries Created Under EU CTR Can Help Shape NIH Policy

  As the NIH shapes its plain language summary policy, EU CTR experience offers practical lessons on clarity, privacy, consistency, and implementation.

• Long-Distance Rare Disease Trials: Why PLL Landed On Australia And New Zealand

  Australia and New Zealand had a lot to offer PLL Therapeutics, but speed and savings aren't the only upsides for running its rare disease trial from its European home.

• Is Moving From One-Off Solutions To A Technology Platform The Best Fit For Your R&D?

  Integrated technology platforms can connect R&D data, accelerate trials, strengthen quality, and cut costs — but successful adoption requires more than AI.

• How Digital Twins Are Reshaping Clinical R&D

  Discover how digital twins are helping predict outcomes, streamline recruitment, reduce patient burden, and accelerate clinical development.