Clinical Pharmacokinetics And Pharmacometrics

The Centre for Human Drug Research (CHDR) offers a sophisticated suite of pharmacokinetic (PK) and pharmacometric services designed to accelerate and optimize early-phase drug development. From timely non-compartmental analyses to advanced population PK/PD modeling and clinical trial simulations, CHDR provides tailored insights to inform dose selection, understand exposure-response relationships, and guide go/no-go decisions.

Our expert team delivers high-quality, regulator-ready reports using validated tools like Phoenix WinNonlin and NONMEM, ensuring full compliance with FDA, EMA, and ICH-GCP standards. With seamless integration into our clinical data systems and collaborations with external bioanalytical labs, CHDR ensures precise data handling and real-time access to concentration-time data. Services include exposure-response modeling, concentration-QTc analyses for cardiac safety, and simulation-supported dose predictions—all rigorously reviewed and executed to the highest standards.