Health Literacy Is The Hidden Enrollment Barrier: How PXO Closes The Comprehension Gap

Health literacy is an overlooked but critical barrier to clinical trial enrollment, retention, and data integrity. Despite regulatory requirements for informed consent, up to 40% of participants fail to fully understand the studies they join, a gap worsened by complex language, emotional overwhelm, and cultural disconnects. Jumo Health’s Patient Experience Optimization (PXO) model redefines consent as a behavioral engagement process, not a document.

PXO addresses comprehension gaps through a layered approach that ensures patients and caregivers receive information in digestible sequences. PXO’s dynamic tools—visual storytelling, real-time comprehension assessments, and personalized decision aids—have driven measurable improvements in enrollment, reduced screen failures, and strengthened regulatory compliance. By transforming consent into an ongoing, adaptive conversation, PXO closes the comprehension gap, enabling more inclusive participation and higher-quality data.

In a landscape where health equity and patient-centered research are imperatives, PXO offers a scalable system to ensure every patient understands, engages, and stays.