How Can Real-World Evidence Inform Clinical Trial Design in Drug Development?

By Ashley Daigneau, Head of Clinical Trials

Explore the transformative role of real-world evidence (RWE) and real-world data (RWD) in streamlining drug development processes, particularly during clinical trials. Traditional trials encounter significant hurdles in participant recruitment and logistical management, often straining resources. RWE offers critical insights that enhance patient selection and optimize trial site logistics, ultimately improving recruitment efficiency. RWE facilitates the anticipation of patient dropout risks and supports adaptive trial designs, allowing for real-time adjustments based on interim findings, which bolsters trial integrity and resource utilization. Beyond recruitment efficiencies, RWE plays a vital role in drug development by identifying biomarkers, risk factors, and potential off-label uses, paving the way for more personalized treatment strategies.

By integrating RWE into clinical trial frameworks, stakeholders can significantly enhance health outcomes and elevate patient quality of life, with organizations such as Verana Health leading the charge in providing essential tools and datasets to realize these advancements.