ISPOR 2026-2027 Top 10 HEOR Trends Report

The healthcare landscape is entering a period of rapid transformation, and the latest Top 10 HEOR Trends highlight where decision makers should focus next. Across global health systems, new pressures—ranging from rising costs to workforce shortages — are elevating the importance of evidence-driven approaches. Artificial intelligence takes the top position, reflecting its accelerating role in streamlining research, enhancing predictive modeling, and reshaping clinical and economic evaluation. Real‑world evidence continues to gain momentum, pushing organizations to strengthen data quality, transparency, and cross‑border collaboration. Emerging priorities such as value-based healthcare, whole‑health measurement, and patient centricity underscore a shift toward care models that prioritize outcomes over volume.

Innovative therapies, digital health tools, and changing drug pricing dynamics add further complexity, requiring leaders to balance affordability, access, and long-term sustainability. As healthcare systems confront unprecedented challenges, HEOR provides a critical framework to guide better decisions — from policy to practice. Explore the full report to understand the forces shaping the next era of health economics and outcomes research and how they will influence strategy across the life sciences landscape.