NeuroCart^®: Measuring A Wide Range Of CNS Effects In A Pharmacological Context

NeuroCart® is an advanced, multifunctional test battery designed to assess a wide range of central nervous system (CNS) functions in pharmacological research. By correlating pharmacokinetic and pharmacodynamic data, NeuroCart enables precise determination of a compound’s efficacy, optimal dosage, and potential adverse effects. This mobile, self-contained system has been validated through extensive clinical use, offering high sensitivity for detecting subtle CNS changes. It includes tests such as saccadic eye movement for alertness, adaptive tracking for visuomotor coordination, EEG for general CNS activity, polysomnography for sleep analysis, and various cognitive and memory assessments.

NeuroCart facilitates early-phase drug development by identifying the therapeutic index, steering between efficacy and safety, and predicting clinical outcomes. It has been instrumental in evaluating sedatives, neuroleptics, and sleep medications, ensuring optimal dosing with minimal side effects. With nearly three decades of successful application, NeuroCart remains a gold standard in CNS pharmacology, supporting precise, data-driven decisions in drug development.