Optimizing A Clinical Development Program To Improve ROI

By Steve Snapinn PhD, Managing Expert, Clinical Center of Excellence

Clinical development proceeds in phases, and each phase contains a set of clinical trials. These trials, including their sample size calculations, are typically designed independently. However, there are advantages to considering the program as a whole and designing it to optimize the study’s return on investment (ROI). Below are some examples where considering ROI benefits individual study designs and the program overall.