Article | January 9, 2019

4 Potential Advantages Of Adaptive Design

By Thomas Laage, M.D., MPH, Director, Product Development Consulting and Regulatory Medical Writing Support

4 Potential Advantages Of Adaptive Design

Adaptive design is a type of clinical trial methodology that incorporates prospectively planned opportunities for modification of one or more aspects of a study’s design or its hypotheses based on interim analysis of study data. Explicitly planning these pre-specified changes helps to maintain scientific integrity while also introducing greater flexibility in the clinical research environment. The major objectives of adaptive design are to make trials more efficient, informative, and likely to demonstrate significant clinical effects in investigational products. And such innovations are necessary in today’s clinical research climate where high attrition rates, lengthy research and development programs, and skyrocketing costs are common.

So far, adaptive design strategies have been especially useful for rare disease research in general and rare oncology in particular. Read more to see how the savvy application of adaptive trial design compares to conventional study designs.

VIEW THE ARTICLE!
Signing up provides unlimited access to:
Signing up provides unlimited access to:
  • Trend and Leadership Articles
  • Case Studies
  • Extensive Product Database
  • Premium Content
HELLO. PLEASE LOG IN. X

Not yet a member of Clinical Leader? Register today.

ACCOUNT SIGN UP X
Please fill in your account details
Login Information
I'm interested in newsletter subscriptions.
ACCOUNT SIGN UP

Subscriptions

Sign up for the newsletter that brings you the industry's latest news, technologies, trends and products.

You might also want to: