Psoriasis: Asia Pacific Clinical Trial Landscape

Psoriasis is a medical disorder where the skin cells proliferate too quickly and flare up, which can be severe or mild. The most prevalent type of psoriasis manifests as scale-like, flaky, silvery-white dead skin cells called plaques, which are elevated, red, and irritating regions. It may impact the genitalia, nails on the fingers and toes, and scalp. Psoriasis is a non-communicable disease, although it may appear to solely affect the skin, it begins inside the body and is brought on by an overactive immune system. (1) Worldwide 2-4% of people suffer from psoriasis. (2) All racial groups have psoriasis, but the prevalence and severity differ. Small plaque psoriasis is unique to the Asian population and severe psoriasis is more prevalent in the Western population. (3) Psoriasis has two peaks of onset, the first at 20 to 30 years old and the second at 50 to 60 years old. (2) Men and women are equally affected. Generally, psoriasis may become worse because of environmental factors like infection, smoking, and specific drugs, yet some patients are more likely to get psoriasis, especially if a family member already has the condition. (2) Stress, skin injury (like a cut or a severe sunburn), an infection (like strep throat), and cold, dry weather are a few examples of common psoriasis causes. These factors can cause the immune system to malfunction and aggravate inflammation, which can exacerbate the symptoms of psoriasis. (4)