Rater Training And Central Rating Services Optimize Signal Detection in Movement Disorder Trial

In a movement disorder trial led by a sponsor, Signant Health's Rater Training & Central Rating services played a pivotal role in enhancing the precision of signal detection for a primary endpoint. This endpoint centered around clinician evaluations of abnormal, involuntary movements in patients afflicted with tardive dyskinesia.

As noted in the case study, Signant's services proved instrumental in enabling investigators to administer a uniform battery of tests for the Abnormal Involuntary Movement Scale (AIMS), thereby ensuring standardization. Subsequently, Signant's blinded central video raters meticulously gauged alterations in AIMS scores from baseline to week 12, fostering a heightened level of accuracy.

Delve into the intricacies of this success story by exploring this comprehensive case study.