Article | October 31, 2018

Replacing The TQT With Exposure-QT Response Study

Source: Medpace
Replacing The TQT With Exposure-QT Response Study

Proarrhythmic Potential For Nonantiarrhythmic Drugs, which introduced the concept of the Through QT (TQT), study was recently revised to include the opportunity to demonstrate the cardiac safety of a new drug by utilizing Exposure-QT response study data in dose escalation and other studies. This now gives sponsors a choice between TQT and Exposure-QT studies.