Retention And Compliance In A Multicenter, Open-Label Clinical Trial

Successful retention and compliance of patients in clinical trials are major challenges in the arduous path to drug approval. Missing outcome data caused by patient dropout and poor compliance not only jeopardize the scientific validity of a study, but also come at a significant financial cost to study sponsors. Technology and behavioral science offer potential solutions that together can address these challenges through patient-centric design of tools such as the Linkt mobile application. This case study examines retention and compliance in a multicenter, open-label clinical trial (N=36).