Article | August 5, 2025

Retention Isn't A Reminder Problem: How PXO Reduces Dropout By Reengineering The Mid-Trial Experience

Source: Jumo Health
GettyImages-904483784 doctor patient

In clinical trials, dropout rates of 15–40% threaten data integrity, escalate costs, and risk regulatory setbacks. Yet, most retention plans rely on passive nudges, ignoring the real reasons patients leave: emotional fatigue, cognitive overload, logistical strain, and feeling forgotten. Jumo Health’s Patient Experience Optimization (PXO) model reframes retention as a dynamic, experience-first strategy that proactively addresses these friction points.

PXO employs four strategic layers to predict and prevent dropout by aligning patient needs with real-time operational support. This method transforms each visit into a reinforcing moment, monitors behavioral signals to forecast disengagement, and delivers tailored interventions that maintain motivation and trust. With retention metrics like the Retention Resilience Index and Dropout Risk Velocity, PXO empowers clinical teams to act before patients disengage. Retention is not about more reminders—it’s about reengineering the trial journey to sustain emotional engagement and operational confidence from enrollment to completion. PXO turns retention into a strategic advantage, ensuring every “yes” becomes a study completer.

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