The Forgotten Stakeholder: Why Caregivers Are The Key To Clinical Trial Success And How A PXO Engages Them Right

Caregivers are often the invisible decision-makers in clinical trials—gatekeepers who influence enrollment, manage logistics, and ensure long-term adherence. Yet, most trial designs overlook caregivers, offering little dedicated communication, support, or burden tracking. This oversight jeopardizes recruitment, elevates screen failure, and increases dropout risk.

Jumo Health’s Patient Experience Optimization (PXO) system repositions caregivers as central stakeholders, delivering a structured engagement model across four dimensions-

• Parallel Education Tracks
• Emotional and Logistical Support Tools
• Burden Visibility and Mitigation
• Caregiver-Centered Outcome Tracking

PXO equips caregivers with tailored materials, decision-support resources, and real-time feedback systems, reducing emotional fatigue and logistical strain while enhancing trial readiness and retention. Metrics such as the Caregiver Burden Index (CBI) and Caregiver Confidence Score (CCS) provide actionable insights into caregiver well-being and engagement risk. Trials using PXO frameworks have demonstrated faster enrollment, lower early dropout, improved adherence, and stronger site performance. By designing protocols and support ecosystems that address caregiver realities, sponsors not only improve trial outcomes but also foster trust and advocacy within family-dependent populations.