Article | October 19, 2020

The State Of Gene Therapy In Dermatology

By Jasmina Jankicevic

Cell and Gene

When it comes to dermatologic conditions, gene therapy is still in its very early stages. However, we are seeing promising potential solutions for some rare genetic dermatology diseases, as well as ongoing research in more common skin conditions.

The success of gene-based therapies relies on three critical elements:1

  1. A well-defined disease gene
  2. A therapeutic gene
  3. An efficient gene delivery system, whether it is a viral or non-viral vector

In our first article, we reviewed gene transfer techniques and gene delivery systems that could potentially be used for treating dermatologic conditions. Now we turn our attention to the current state of gene therapy for dermatologic conditions.

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