Turning Precision Into Predictability: How Trial Compass Is Solving Psychiatric Trial Enrollment
Psychiatric trials have long been among the most difficult to enroll. From treatment-resistant depression (TRD) and PTSD to cognitive and neuro disorders, sponsors are facing the same challenges over and over again:
- Narrow I/E criteria that don’t translate into real-world patients
- Sites with limited behavioral health infrastructure
- Lack of patient trust and trial awareness in psychiatric populations
- Professional patients
- Rating scales aren’t used in clinical practices
But what if recruitment didn’t have to start with a gamble?
Enter Trial Compass — a new approach from CSSi that eliminates the guesswork from psychiatric enrollment. Built in partnership with Beacon Behavioral Health Partners, one of the fastest-growing behavioral health practices in the U.S., Trial Compass uses AI-enhanced EHR mining, physician-directed outreach, and a local referral transfer system to give sponsors a a lane to claw back recruitment timelines in rescue situations, as well as on prospective studies planning and recruitment plans.
The Power of Pre-Screened, Physician-Approved Patients
At the core of Trial Compass is a unique operational advantage: real-time access to Beacon’s EHR network of deeply characterized psychiatric patients, all of whom are under active care. These aren’t abstract leads from digital campaigns—they’re real patients, known and supported by their providers.
With the AI-powered Beacon EHR engine, CSSi can identify patients by diagnosis, treatment history, medication washouts, comorbidity flags, and more—then notify the treating physician directly to initiate a warm handover to a research site within proximity.
Local, Trusted Referrals—at Scale
Trial Compass is active across Beacon’s 50+ locations nationwide, which means sponsors can instantly plug in to psychiatric patient pipelines in key markets. When trials overlap with Beacon locations, CSSi is able to offer:
- Physician-confirmed referrals that match protocol criteria
- Warm handoffs to sites within defined miles of the patient’s origin
- Local Enrollment Specialists to guide patients and site staff through screening
The result? Faster startup, fewer screen fails, and dramatically improved site satisfaction.
No Risk. No Delay. No Guesswork.
Trial Compass is built on a performance-based pricing model: CSSi and Beacon assume 100% of the recruitment risk. Sponsors pay only for qualified consents or randomizations. There’s no media spend, no retainer fees, and no wasted weeks hoping for digital ad conversions.
And we’re asking the industry one simple question:
If you’re running a psychiatric trial near a Beacon site… why wouldn’t you turn this on?
Not Just Recruitment. A Site Selection Strategy.
Trial Compass isn’t just an enrollment tactic—it’s a site optimization strategy.
With real-time visibility into active psychiatric populations, CSSi and Beacon can help sponsors prioritize future sites based on referral density, diagnosis volumes, and historical enrollment success.
That means smarter startup, less site underperformance, and faster first-patient-in.
The days of guessing your way through psychiatric recruitment are over. Trial Compass is how the industry gets back on course.