Clinical research studies involving repeated patient reported outcome measures (PROs) face several challenges. Patients may fail to complete individual PROs, whether at all or within a specified time (i.e., reduced compliance). Patients may cease participating in a study altogether, dropping out before all study procedures are completed (i.e., reduced retention). Sponsors must consider strategies to maximize participant retention and compliance to avoid loss of PRO data relevant to study endpoints and to avoid financial and operational burdens associated with participant loss to follow-up (e.g., needing to enroll additional patients to capture sufficient safety follow-up data).
Through Datacubed Health’s Linkt app, participants can easily complete PROs via their smartphones. Several features are available within Linkt to assist study staff with ensuring high participant retention and compliance, including configurable reminders to complete instruments. Linkt leverages behavioral science to sustain high compliance and retention rates, with several tiered motivational elements for short, medium, and long-term studies.