When Do I Need A DMC?

To better understand when you may need a data monitoring committee (DMC), it’s helpful to know a DMC’s role in research.

• A DMC, also referred to as data safety monitoring board (DSMB), is an independent group of experts who conduct a periodic review of accumulated worldwide clinical data during a clinical trial.
• The primary purpose of a DMC is to report early evidence of benefit or harm in a study, accounting for the safety of participants and integrity and validity of the data.