Where The Data Starts: Rebuilding Sponsor-Site Alignment On Source

Every data point in the clinical database starts somewhere, but the path from patient visit to system entry is often more complex and risk-laden than sponsors realize. When sponsor expectations do not align with site realities, the result can be missing data, unnecessary queries, duplicative work, and added reconciliation burden.

In this candid conversation, Greg Manning, Head of Centralized Network Operations at Atlas Clinical Research, joins TruTechnologies’ Peter Brown and Collier Wright to discuss the disconnect between sponsor-designed data systems and the way source data is actually created, managed, and verified at the site.

Together, they explore why source data alignment matters even more under ICH E6(R3), and what sponsors need to understand about transcription, validation, PI oversight, and the operational burden created when sites are asked to enter the same information in multiple places.