preclinical white papers and articles

  1. Continuing Your Research Mission -- Even As Budgets Tighten 5/12/2025

    Amid growing uncertainty in clinical research funding, including proposed budget cuts from the NIH that threaten indirect support for essential infrastructure, OpenClinica remains a steadfast partner to researchers.

  2. Journey Of A Therapeutic Antibody 5/2/2025

    Delve into the early development journey of a therapeutic antibody and learn about the critical role of robust biomarker strategies and analytical assays.

  3. The Evolving Landscape Of Radiopharmaceuticals In Oncology Research 4/24/2025

    From selecting appropriate targeting molecules to optimizing dosing strategies and managing off-target effects, radiopharmaceutical development demands a tailored and strategic clinical approach.

  4. Blueprint For Early Phase Clinical Pharmacology Studies In Dermatology 4/11/2025

    Explore the landscape of dermatological drug development through a comprehensive framework for rational early-phase dermatological trials, centered around five foundational pillars.

  5. Bladder Cancer: Challenges And Innovations 4/4/2025

    Bladder cancer ranks ninth in incidence and 13th in mortality among cancers. Recent advancements in treatment are transforming the management of advanced bladder cancer cases.

  6. Safety Assessment For Ophthalmic Products 2/20/2025

    Dive into the world of ophthalmic drug development, where careful considerations in the preclinical phase must be taken to facilitate advancement into first-in-human clinical trials.

  7. Comprehensive Services For Ophthalmic Drug Development 2/20/2025

    To maximize bioavailability while preserving vision and maintaining the structural integrity of the eye, formulation and delivery strategies must be meticulously designed.

  8. Overview Of Triple-Negative Breast Cancer: Global Clinical Trial Landscape 1/30/2025

    Triple-Negative Breast Cancer (TNBC) requires new and innovative treatments, such as biomarker-driven therapies, to enhance precision medicine and improve patient outcomes.

  9. Oncolytic Virus Therapy: Insights Into Clinical Trial Landscape And Industry Trends 1/30/2025

    Answering questions about the potential of oncolytic virus therapies, how they integrate with combination therapies, the regulatory landscape, and how it varies globally.

  10. Oncolytic Virus Therapy: Global Clinical Trial Landscape (2024) 1/30/2025

    Addressing immunological challenges and navigating the evolving regulatory environment is critical for its successful integration into clinical practice.