Accelerating Patient-Centric Trials: A Sponsor's Checklist For Patient-Centric Success

Effective trial success in today’s complex research environment requires early, science-driven planning and patient-centered design. This checklist will help you to strengthen planning, elevate patient engagement, and drive submission success.

Sponsors can improve enrollment feasibility by involving cross-functional teams early, streamlining inclusion/exclusion criteria, leveraging real-world data, and validating assumptions through feasibility pilots. Early regulatory engagement also helps avoid costly mid-study amendments. Hybrid models that blend home-based assessments with site visits can enhance recruitment and retention, and centralized technology platforms enable real-time monitoring of site performance and patient engagement.

Rapid responses to patient inquiries significantly boost referral-to-consent conversion, and proactive retention strategies at startup help sustain participation. Streamlined data operations, parallel workflows, and integrated engagement tools further minimize site burden and accelerate submission timelines. Programs that combine rapid patient response with companion support achieve up to seven times higher conversion rates, highlighting the value of pairing operational efficiency with genuine patient support.