As the name indicates, a centralized site model allows patients to be treated at one or two central sites, which minimizes the travel burden on patients and caregivers. A combination of technology and/or mobile staff are employed to conduct follow-up visits in a convenient local setting or at the participant’s home. This model supports Veristat’s patient-centric philosophy, reducing the burden for trial patients while providing an innovative solution for sponsors. Benefits include greater consistency and operational efficiency that is more manageable and saves costs. Centralized trials are especially beneficial for rare disease programs.