Newsletter | October 14, 2026

10.14.26 -- Can We Make Feasibility More Realistic?

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Join our webinar on October 22, 2026, at 11 AM ET to learn how to successfully execute adaptive trials. We will explore key impacts on sites, data, technology, supply, and teams. Don't let adaptation turn into disruption—register today to secure your spot! Registration is free.

TRIAL MANAGEMENT

Can We Make Feasibility More Realistic?

Drawn from a Clinical Leader Live webinar, this article explores how sponsors can make clinical trial feasibility and enrollment forecasts more realistic by questioning data sources, examining patient and site burdens, challenging protocol assumptions, and looking beyond seemingly convincing answers from historical data and AI.

Déjà vu? A Decade At AAIC, And The Endpoints Haven't Moved

Cognitive endpoints in Alzheimer's trials haven't kept pace with the shift to earlier-stage treatment. Modern trials need tools built to catch subtle change.

CRF Validation Best Practices: Building Reliable Clinical Trial Databases

CRF validation improves data quality and efficiency. Early planning, clear edit checks, and balance reduce rework, ease site burden, and enable more reliable, streamlined study execution.

Anthropic's Stainless Acquisition: What It Means For Clinical Trials

As AI models become interchangeable, value is shifting to the orchestration layer that connects tools, workflows, and governance—making flexibility, interoperability, and auditability critical.

Packaging As Strategy: Enabling Clinical-To-Commercial Success

Explore how strategic, integrated packaging can accelerate clinical-to-commercial success while enabling patient-centric, scalable, and globally resilient drug delivery.

IRT: A New Approach To Meeting The Needs Of Early Phase Trials

As early phase clinical trials become more sophisticated, sponsors are now leveraging flexible IRT solutions to replace error-prone manual processes and gain greater control and efficiency.

Early‑Phase Autoimmune Drug Development

Adaptive designs and biomarker tracking help early autoimmune trials find true signals despite complex, variable disease patterns.

Deliver Supply Without Friction. Maintain Control At Every Step

Learn how clinical supply organizations can reduce manual effort, strengthen compliance, improve global coordination, and maintain control across evolving clinical trial supply chains. 

DECENTRALIZED TRIALS

The Rise — And Stall — Of Retail Pharmacy Clinical Trials

As rumors swirl that Walgreens may be reassessing its clinical trials business, this article explores a broader trend: why major retail pharmacy chains like CVS, Walmart, and Kroger have struggled to make the model work at scale.

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