Delivering Specialist Neurology Support: MRN's Multinational Parkinson's Disease Trial Expertise

Parkinson’s disease presents significant clinical trial challenges due to its progressive nature, fluctuating symptoms, and the need for intensive monitoring—particularly during critical intervention periods such as drug titration via jejunal tubes. To address the complexities of conducting a global, high-intensity Parkinson’s disease trial, MRN deployed a rapid-response network of multilingual neurology-specialist nurses across nine countries, often within 24 hours’ notice. These professionals delivered precise, hourly neurological assessments during a 10-day titration phase, while providing hands-on training to both patients and site staff to ensure accurate use of complex medical devices.

MRN’s strategic approach leveraged its global infrastructure and multilingual workforce to provide seamless operational and clinical support, minimizing site burden and ensuring compliance with strict protocol demands. Through this model, MRN enhanced patient safety, ensured data consistency, and empowered sites to focus on patient-centric care. Here we underscore the vital role of specialized, flexible resourcing in overcoming the operational and logistical challenges inherent in multi-country Parkinson’s trials, and the potential for scalable, expert-driven support models to optimize trial outcomes and accelerate research in complex neurological disorders.