Driving A High-Adherence LTFU Trial Without An EDC

A leading contract research organization (CRO) partnered with an innovative clinical technology provider to conduct a long-term follow-up (LTFU) observational trial spanning multiple decades and countries. Unlike shorter, tightly controlled studies, long-term observational research faces unique challenges — from evolving medical standards to changing technologies and regulations. Traditional electronic data capture (EDC) systems, while reliable in conventional trials, often lack the flexibility required for such extended timelines. Maintaining them demands large specialist teams, complex integrations, and high operational costs, especially when consolidating data from diverse global sources.

To address these challenges, a modern, cloud-based approach was implemented; one designed for scalability, compliance, and adaptability over time. The result was a streamlined system that reduced costs, simplified operations, and maintained remarkable participant engagement, achieving a 97% patient retention rate.

This case demonstrates how forward-thinking data strategies can redefine the future of large-scale, long-duration clinical research, thus empowering organizations to run smarter, more efficient trials that stand the test of time.