High Density, Low Availability: Rethinking Ophthalmic Trial Readiness

The evolving landscape of ophthalmic assessments in clinical trials presents unique challenges, especially in regions known as "eye care deserts," where the infrastructure for advanced research is insufficient despite high concentrations of eye care professionals. Here we focus on the strategic considerations for ophthalmologists and sponsors conducting trials in these areas. While states like Florida, California, and Texas boast numerous ophthalmology practitioners, many lack the necessary resources, such as advanced imaging equipment and specialized staff, due to geographic clustering and high patient demand. Optometrists, though plentiful, often do not possess the specialized tools required for sophisticated trial endpoints, further complicating the landscape.

To mitigate these challenges, the adoption of mobile ophthalmic solutions and collaboration with specialized vendors is recommended to ensure trial consistency and reach underserved regions. This approach underscores the critical need for comprehensive site feasibility assessments and strategic partnerships with academic centers and specialized clinics. Recognizing the existence of "eye care deserts" in densely populated areas is vital for effective resource allocation and trial execution. Ultimately, the mere presence of an ophthalmology community is insufficient; strategic resource planning and deployment are essential for robust clinical research.