MRN's Decentralized Trial Data Handling

The purpose of eSource is to improve the quality of data collection, by automatically reducing errors and increase efficiency by reducing the required review process as much as possible.

MRN’s eVRF (e-visit report form) is an electronic form, tailored to match the needs of each clinical trial, used to capture subject and clinical data during the Home Trial Support visit. The eVRF is completed via a secure app. deployed on MRN provided, iPads. This is then uploaded directly onto the eSource platform at the end of the Home Trial Support visit or as soon as the healthcare professional has the connectivity to load following the completion of a visit.

Uploaded eVRFs are reviewed by MRN, starting the quality management/data clarification process. The eVRFs are reviewed based on criteria agreed with you and will include a mixture of logic and gap checks. To drive efficiency and quality many checks will be enforced automatically during the completion of the eVRF, whilst more complex checks can be agreed based on personal monitoring and data management guidelines. MRN and site staff are granted access rights based on their functions to the eSource platform. This allows them to review the visit data once it has been recorded and uploaded.

The site will have access to eVRF data within 48 hours of the visit when data is in review. This allows the subject data to be medically reviewed by the site, including visit confirmation, and allows an assessment of the healthcare professional’s performance. Sites will be able to raise queries and see all updates and responses as queries are resolved during the MRN review.

We are rolling this new platform and system out across our portfolio and new projects.