Florence accelerates clinical research with innovative solutions to streamline clinical trial site workflows and remote connect sponsors, CROs, and sites for access, monitoring, management, and SDR/V. The Florence platform is the industry standard with more than 7,200 research sites in 27 countries, sponsors and CROs collaborating on its network.

Research study sites manage their internal document operations with the #1 Electronic Investigator Site File with solutions across eRegulatory, Source Capture, eConsent, eLogs, Contract Management, SOP Management, and Remote Access.

Sponsors and CROs gain unprecedented remote access to their study sites for remote startup, monitoring, and SDV built on the industry-standard remote site access platform.


Florence eTMF is designed to give you all the capabilities you need in an intuitive and flexible interface. Plus, you get remote digital connection to 7,200 research sites managing their eISF on our network, with the ability to deploy the #1 digital site workspace to all of your study sites.

Successful clinical trials require remote site access and collaboration. We’ve got you covered. Florence eHub gives Sponsors and CROs direct digital access to the network of 7,200+ Investigator sites across 26 countries managing their eISF on our platform. Plus, our expert site digital transformation team works with you to get your other sites online fast – in as little as three days.

Florence eBinders integrates all of your clinical trial systems, automates eRegulatory processes, reduces contract negotiation time, tracks study progress, and enables secure remote monitoring on the industry-standard eRegulatory, eISF, and eSource platform.


Florence Healthcare

600 Peachtree St. NE, Suite 920

Atlanta, GA 30308


Phone: 706-768-2196

Contact: Blake Adams


  • The failure to prioritize the TMF can leave sponsors and clinical research organizations (CROs) to appear disorganized, delay clinical trial completion, and, in the worst cases, fail at bringing treatments to market. Sholeh Ehdaivand, president and CEO of LMK Clinical Research Consulting, discusses the Trial Master Files (TMF) and its pivotal role in the future of real-time collaboration between clinical research sites and sponsors.

  • Remote site access is now a requirement for clinical trial operations. As you seek to transform your monitoring strategy and build your virtual toolkit, you must must be familiar with the capabilities available. The failure of a remote site access solution will result in disrupted site workflows, increased compliance risk, and ultimately delayed study timelines. The Florence team put together this list of requirements most sponsors and CROs look for in their selection process to help you make an informed investment in this new technology category.

  • Biotech companies starting their first few clinical trials typically do not have the resources to host an eTMF in-house. For this reason, they often outsource to a Clinical Research Organization (CRO) and use the CRO’s applicable software. If the study is successful and moves to subsequent phases, or if Biotech adds new studies to their portfolio, hosting the eTMF with subcontractors limits the Biotech from moving operations in-house or engaging new CROs. Continue reading to learn more reasons why Biotech companies are bringing their eTMF in house even if they outsource services to subcontractors.

  • The COVID-19 pandemic has accelerated the ongoing shift to remote clinical trial monitoring. In this article, we explore challenges of traditional monitoring, benefits of remote clinical trial monitoring, how to deploy remote clinical trial monitoring, sponsor-deployed remote monitoring technology, and site-procured remote monitoring technology.

  • How are clinical operations leaders making strategic technology investments in 2021 and beyond? This report provides insights from more than 200 respondents to the annual Florence State of the Industry Survey, from dozens of stakeholders who are members of the Florence Executive Advisory Board, and more than 8,500 study sites and more than 8,000 sponsors using Florence.

  • Sites, sponsors, and CROs now perform the bulk of their clinical trial operations by logging into cloud-based systems. Direct digital connectivity and collaboration access with your sites, via connecting to the largest Electronic Investigator Site Files (eISF) in research, eliminates clinical trial bottlenecks.

  • In a world with more data and less time, the advantages of cloud-based technologies are hard to ignore. Debunk some of the common misconceptions of managing clinical research documents, data and workflows in a cloud-based technology platform.

  • Today’s modern clinical trial requires robust and purpose-built eClinical solutions. One of the essential capabilities you must ensure exists is the ability to integrate with other systems through Open APIs.

  • Sponsors and CROs’ ability to access and collaborate with a research site is essential to the success of every study. As study sites “come on-line,” Sponsors and CROs are in a unique position to harness this digitally connected network of sites to turn on remote site access and Source document review/verification (SDR/V), and streamline workflows. In this article, we examine the key quality outcomes and technology recommendations associated with digitally accessing the site eISF.

  • The Electronic Investigator Site File (eISF) Reference Model is the industry standard for setting up and managing an Electronic Investigator Site File. The rise in the eISF, coupled with an increasing need for real-time collaboration and document exchange among sites and sponsors/CROs, mandates the need for an eISF Reference Model. Here are six benefits of an eISF Reference Model.

  • Sites, sponsors, and CROs now perform the bulk of their clinical trial operations by logging into cloud-based systems. As you evolve your monitoring and site management strategy to a remote approach, we are providing you with the 5 essential considerations to focus on to ensure site acceptance, site adoption and a successful implementation of your remote strategy.

  • Remote site monitoring platforms are now a requirement in clinical research operations. While accelerated to mitigate COVID disruptions to site-access, the pivot to remote site access will be the new normal. This article highlights how to select the remote site monitoring solution for your clinical trial.

  • Not all sponsors and CROs that select and implement an Electronic Trial Master File (eTMF) solve the bottlenecks and inefficiencies that the system was selected to target. Why? Often, during the vendor selection process, organizations undervalue the need for site acceptance, disregard the impact of vendor support teams, overlook critical implementation processes, and don’t fully understand the correlation between software capabilities and the bottlenecks they address. This article addresses some common friction points and how to address them.

  • Remote site access, monitoring, and SDR/V are essential to mitigate COVID-19 disruptions to clinical trials in the short-term and to accelerate the research industry in the long-term. However, one doesn’t have to look far to find failed attempts at remote site monitoring. As an industry we are positioned – and poised – to get it right this time around, this article explores insights as to how to avoid these failures.

  • As the number of global clinical trials continues to rise it is important to understand the global compliance requirements needed for technology being utilized by your organization. This knowledge will empower you to select vendors that adhere to these requirements and support your ability to take on studies or scale participating sites regardless of their geolocation.

  • Today’s crisis climate is creating a dichotomy in clinical research. As a result, sites are closing, medical facilities are enforcing access restrictions, and there are constant delays or stoppage of non-essential studies. On the other hand, this health crisis is highlighting the critical need for clinical research due to ongoing COVID-19 trials. As a result, clinical researchers are asking questions and seeking workarounds to continue operations in response to site-specific adjustments. One central issue has surfaced — how do we continue to maintain compliance when working from home?

  • COVID-19 radically disrupted clinical trial operations and forced an acceleration of the transformation agendas leaders had in place pre-crisis. While the acceleration of pre-crisis transformation agendas in clinical trial operations will be measurable, it will not leap to a 10+ year horizon. This blog takes a deeper dive into these changes and how it will affect the industry.

  • Implementing an eTMF is critical for Sponsors and CROs that want to reduce burden, increase study capacity, and enable more trials. However, many organizations are not equipped with a modern solution to realize the full benefit and future proof operations. This guide serves as an in-depth overview of how a modern eTMF solution can impact your organization and the steps you can take to prepare.

  • Shifting to eRegulatory and eSource workflows is a requirement for clinical trial sites to continue to scale and grow their studies. However, many site leaders are not fully prepared for the transition. This guide is designed as an in-depth overview of how eRegulatory and eSource are impacting clinical trials, and the steps you can take to prepare now.

  • The ability to access and collaborate with a research site is essential to the success of every study. A disconnected mix of on-site visits, email communications, and portals restrict site access and document exchange for Sponsors and CROs alike. Read how remote site access, source document review/verification and streamlined workflows transforms essential clinical trial processes.