Insights On Trial Design

  1. Phase I Clinical Trial Designs: Bayesian Logistic Regression Model (BLRM) 9/25/2025

    The Bayesian Logistic Regression Model (BLRM) is redefining Phase I clinical trial design by bringing flexibility, precision, and patient-centered safety into early drug development.

  2. How Different Are Oncology Clinical Trials? 3/19/2024

    Oncology clinical trials pose unique challenges. Dive into five key reasons behind the intricacies of oncology trials, from recruitment hurdles to data volume and efficacy endpoints.

  3. Leveraging Real-World Data From The IRIS® Registry 7/8/2025

    With the FDA’s new Diversity Action Plan requirements, sponsors are now expected to set clear goals and strategies for enrolling diverse populations in clinical trials.

  4. Achieving End-To-End Clinical Supply Chain Visibility 9/23/2025

    Transform supply chain management by integrating technology solutions and real-time insights to link patient-level data with upstream manufacturing operations.

  5. Real-World DHT Adherence Insights And Good Practices 7/10/2025

    While advances in sensors and device design are improving wearability, successful data collection still hinges on participant adherence. The session highlights why addressing this can’t be an afterthought.

  6. Market Fragmentation In Clinical Trial Recruitment Organizations 9/17/2025

    The fragmented clinical trial recruitment market presents challenges, but a strategic approach with platform-based solutions can streamline processes and accelerate research.

  7. Epidermolysis Bullosa: Future Perspectives In Drug Development 1/14/2025

    Recent breakthroughs are signaling a promising shift in the landscape of Epidermolysis bullosa (EB) care from focusing on pain management to a growing commitment to curative strategies.

  8. Faster, Smarter Start-Up: Launch Trials Without Bottlenecks 8/18/2025

    By pairing proven practices with modern technology, trials reduce start-up delays, cut costs, and ensure treatments reach patients faster.

  9. The Impact Of An AI Enabled Consent Process 5/15/2024

    In this episode of Download with Derk, we take an in-depth look at our internal experiment where Castor Companion was utilized during the consent process.

  10. Local Considerations When Developing sIRB Reliance Policies 6/17/2024

    Delve into the importance of training and educating research staff on the sIRB process, fostering a culture of collaboration, and developing mechanisms for monitoring compliance and managing conflicts.