Trial Design

INSIGHTS ON CLINICAL TRIAL DESIGN

Advancing Dose Escalation Strategies With Bayesian Modeling
A CRO was engaged to help a biotechnology sponsor develop a novel oncology therapy design and execute a multicenter, open-label Phase 1/2 dose escalation and expansion study in advanced solid tumors.
What Clinical Trial Decision Makers Are Prioritizing In 2025
In 2025, clinical trial operations are undergoing a transformative shift driven by the need for speed, cost-efficiency, and patient-centered approaches.
"We'll Figure It Out Later" Is Where Trial Friction Begins
Delayed operational decisions around travel, payments, site workflows, meetings, and compliance can create avoidable friction for sites, participants, sponsors, and CROs once a study is underway.
Virtual eConsent For Decentralized Trials
Virtual eConsent improves accessibility and compliance in decentralized trials, streamlining enrollment with a secure, user-friendly process for informed consent in remote research.

RTSM Rescue Studies Are On The Rise
5/26/2026

As RTSM technology continues to evolve, clinical trial rescues are becoming increasingly common. Explore the rise of the rescue trend and why more sponsors are ready to change course.
Clinical Leader Smart Sourcing Solutions Expo: Mural Health Removing Barriers To Trial Participation
10/28/2025

Learn how one platform is transforming the participant journey to deliver a 60% reduction in participant drop-out and 97% engagement rates, improving retention for even the most vulnerable populations worldwide.
Vendor Selection Bias: Why Structured Decisions Often Fail
12/22/2025

Learn how subtle influences derail decisions and discover proven safeguards that promote transparency, accountability, and shared ownership for better trial outcomes.
Redefining Accessibility For Pediatric Patients
9/24/2025

Explore how meeting patients where they are can redefine what successful pediatric trial delivery looks like.
Clinical Research Logistics: How Point-Of-Need Execution Protects Ocular Endpoints
6/9/2026

Reduce operational risk in ophthalmic trials with point-of-need execution. Discover how mobile clinics, specialized teams, and single-call accountability protect endpoint quality and study timelines.

Making The Impossible Possible In Oncology And Hematology Clinical Development

When the complexities of designing and executing cancer trials in a highly competitive market can mean delays in delivering urgently needed treatments to patients, it pays to have a trusted partner by your side.
Central Nervous System Drug Development

CNS drug development faces unique hurdles — from high placebo response to complex protocols and recruitment challenges. Discover strategies to streamline trials, optimize planning, and accelerate delivery of innovative therapies for patients with critical unmet needs.
Smarter Oversight, Earlier Action

When risk-based oversight is reduced to a compliance checkbox, critical signals can be missed and escalate into systemic issues.
Get It Right The First Time: Strategic Clinical Development

Start early and get it right the first time. Course correct with a changing landscape. Overcome obstacles within clinical development. Collaborate with the best strategists and problem-solvers in clinical development.
Subject Eligibility Review: Enrolling The Right Subjects

Screen failures, dropouts, and protocol deviations start with the wrong participants. A holistic eligibility review process helps get enrollment right the first time.