Trial Design

INSIGHTS ON CLINICAL TRIAL DESIGN

Recruitment Worked. Can Participants Actually Stay In The Study?
Enrolling in a clinical trial doesn’t settle how participants will attend future visits. Upfront expenses and recurring travel needs can expose gaps in study support.
Addressing Trial Design Hurdles Across Alzheimer's Disease Stages
Explore how endpoint selection, rater training, and the strategic implementation of eCOA can help address the unique scientific, operational, and human considerations at each stage of AD.
The Ten Commandments Of Vendor Management
Master trial governance with 10 core principles. Learn how tracking trends, rewarding transparency, and early escalation ensure long-term trial success.
Transforming Ophthalmic Assessments For A Mid-Trial Protocol Change
Discover how a biopharmaceutical company integrated urgent mid-trial mandates across 65 sites, cutting standard onboarding timelines in half while preserving critical enrollment milestones.

The Role Of FDA Initiatives In Early-Phase Oncology Trials
5/15/2025

Project FrontRunner represents a paradigm shift in oncology drug development, championing earlier-line studies to bring novel treatments to patients sooner.
How Home Trial Visits Support Sites And Patients
3/20/2025

By reaching into the heart of communities, Home Trial Support plays an invaluable role in driving the development of lifesaving, representative, medicines and therapies.
Why Community-Rooted Recruitment Is The Future Of Clinical Trials
4/10/2025

Despite clinical trial awareness campaigns and site expansions, trials continue to fall short in reaching the patients who need them most, resulting in a shift toward community-rooted recruitment.
How RWD Reshapes Patient Recruitment Strategies
8/13/2025

Discover how real-world data (RWD) is transforming patient recruitment by shifting from traditional site-centered methods to a patient-first approach.
Expectations For Plain Language Summaries Continue To Evolve
11/7/2025

Plain language summaries (PLS) are growing in importance as a requirement in global transparency. Focusing on protocol and results summaries, we cover expectations and best practices for global PLS implementation.

Patient Travel And Logistics

Block Clinical provides a single point of contact for Patients and Sites who support them throughout their journey, from start to finish.
Patient Liaison: Per-Visit Participant Support

Dedicated Patient Liaison support helps coordinate participant travel, reimbursements, and visit logistics so sites stay focused and study requests keep moving forward.
Biostatistics: End-To-End Management

Discover how a team of biostatistics and pharmacokinetics experts can offer specialized guidance for clinical trial design and analysis.
Intelligent Trials - Diversity

Medidata AI’s Intelligent Trials solution provides insights that allow you to take action to improve study diversity during the planning stages.
How Trial Compass Is Solving Psychiatric Trial Enrollment
Psychiatric trials have long been among the most difficult to enroll. From treatment-resistant depression (TRD) and PTSD to cognitive and neuro disorders, sponsors are facing the same challenges over and over again:
- Narrow I/E criteria that don’t translate into real-world patients
- Sites with limited behavioral health infrastructure
- Lack of patient trust and trial awareness in psychiatric populations
- Professional patients
- Rating scales aren’t used in clinical practices
But what if recruitment didn’t have to start with a gamble?