Trial Design

INSIGHTS ON CLINICAL TRIAL DESIGN

Human Abuse Potential: Subjective Ratings
Accurate subjective ratings are central to Human Abuse Potential studies. Learn how Visual Analog Scales are administered, what influences responses, and why data collection practices are essential.
Supporting Participants Through National Travel Disruptions
A sudden travel shutdown threatened a critical clinical visit. Rapid rescheduling, coordinated logistics, and clear communication ensured engagement and the ability to continue without interruption.
Winning Enrollment In A Competitive CNS Trial Landscape
Many CNS trials today operate in a highly competitive environment. Enrollment success is shaped by the decisions teams make under these constraints.
Why RWD Strategy Can't Wait With Price, Value And Evidence Pressures Everywhere
Overcome pricing pressures and reimbursement delays by integrating real-world evidence early in development to align clinical outcomes with payer demands and accelerate patient access.

No More Swiss Holes: Filling The Gaps In Clinical Trial Disclosure
1/14/2026

This use case shows how sponsors can gain clarity on disclosure requirements when entering a new country.
Why Team Integration Makes Or Breaks Marketing Applications
4/10/2025

True team integration transcends basic collaboration, requiring the dismantling of barriers between sponsors and vendors, eliminating departmental silos, and cultivating mutual accountability.
Trends In Clinical Trials In 2025: Navigating A Transformative Landscape
1/22/2025

In 2025, it is likely the clinical trial landscape will be shaped by advancements in artificial intelligence (AI), evolving recruitment strategies, and a renewed focus on equitable access.
5 Essential Steps To Implementing Decentralized Clinical Trials Globally
9/15/2025

Running a global decentralized clinical trial requires a strategy that balances the FDA's focus on technology accessibility with the EMA's emphasis on validation and comprehensive documentation.
5 Strategies For Designing Successful Complex Rare Disease Trials
3/31/2026

Rare disease trials demand inventive design. Uncover creative strategies that help sponsors overcome tiny populations, complex endpoints, and operational hurdles to advance meaningful breakthroughs.

Unify Workflows And Accelerate Execution From Protocol To Submission

Explore a platform that benefits the entire global clinical trial ecosystem by reducing complexity and operational costs while maintaining the highest standards of data security and subject privacy.
Castor Professional Services: Your Trial Delivery Partner

Accelerate clinical trial timelines and ensure audit-readiness with expert-led build models, AI-driven data management, and global participant support designed to streamline your path to submission.
Accelerate Clinical Trial Cycle Times With Citeline Study Feasibility

Citeline Study Feasibility is a platform that combines subject-matter expertise and machine learning to develop predictive insights for feasibility planning. Clinical trial sponsors can use these insights to identify key data drivers and model their impact, build and simulate feasibility scenarios, accelerate timelines, and make better decisions than with statistical methods alone.
User Acceptance Testing (UAT): Keeping Trials On Track

Validate endpoint performance and security before deployment with structured UAT that reduces risk, ensures compliance, and enhances user experience through real-world testing.
De-Risk Randomization With The Endpoint Biostatistical Approach

With over 15 years of RTSM experience, high-touch quality management, and forward-thinking technology, our solutions enhance trial speed, accuracy, and operational efficiency.