INSIGHTS ON CLINICAL TRIAL DESIGN

• Busting Through Patient Recruitment Barriers

  Building patient trust fuels engagement, data and technology enable targeted recruitment, and real-time patient identification with consistent support drives scalable enrollment success.

• Why Operational Design Determines Recruitment And Retention

  Patient recruitment challenges often receive the most attention in clinical trials, yet many enrollment and retention issues stem from operational friction embedded in study design.

• Leading Recruitment With A Strong Alzheimer's Referral Pool

  A strong referral network helped the Gainesville site rapidly recruit pTau217‑positive Alzheimer’s participants while upholding high data quality, boosting enrollment and outperforming other sites.

   

• Phase I Clinical Trial Designs: Continuous Reassessment Method (CRM)

  The benefits are clear: CRM accelerates dose finding, reduces patient exposure to unsafe doses, and improves trial efficiency.

• The Psychedelic Setback: What MDMA Rejection Taught Drug Developers

  6/25/2026

  Psychedelic compounds show real promise for PTSD, but proving it requires solving unblinding, bias, and safety gaps in trial design.

• Overcoming Barriers To Clinical Trial Participation In Oncology

  12/3/2024

  Oncology clinical trials face unique challenges in patient recruitment and retention due to barriers such as awareness, logistical constraints, and eligibility criteria.

• Advancing Dose Escalation Strategies With Bayesian Modeling

  8/12/2025

  A CRO was engaged to help a biotechnology sponsor develop a novel oncology therapy design and execute a multicenter, open-label Phase 1/2 dose escalation and expansion study in advanced solid tumors.

• Clinical Trial Support: Point Of Need vs. Traditional Solutions

  7/24/2025

  Examine the limitations of traditional, fixed-location ophthalmic trial sites and how a mobile assessment model can significantly improve patient retention while ensuring high-quality data collection.

• Human Abuse Potential: Subjective Ratings

  5/5/2026

  Accurate subjective ratings are central to Human Abuse Potential studies. Learn how Visual Analog Scales are administered, what influences responses, and why data collection practices are essential.