Newsletter | October 28, 2026

10.28.26 -- The U.S. Clinical Trial Recruiting Pipeline – September 2026

TRIAL MANAGEMENT

The U.S. Clinical Trial Recruiting Pipeline – September 2026

This WhichTrial report breaks down which drug trials are growing the most and the least, drugs that are no longer being studied, and new drugs to the clinic from August to September.

Optimizing The Path From First-In-Human To Proof-Of-Concept

By collapsing the gaps between manufacturing and clinical trials and integrating these functions into a unified system, teams can adjust formulations in real-time and accelerate timelines.

IRT: A New Approach To Meeting The Needs Of Early Phase Trials

As early phase clinical trials become more sophisticated, sponsors are now leveraging flexible IRT solutions to replace error-prone manual processes and gain greater control and efficiency.

Reserving Data Integrity With Retrospective Manual Entry

A look at implementing randomization mid-trial by reconstructing subject and inventory records without disrupting sites or compromising data integrity.

Accelerate Shipment For SCN1A+ Dravet Syndrome Gene Therapy

Consider this streamlined, end-to-end solution that helped safeguard study timelines and ensured that patients with urgent medical needs could receive treatment without delay.

How Adaptive Design Accelerates Early‑Phase NSCLC Development

Adaptive trial designs and an adaptive mindset enable non-small cell lung cancer (NSCLC) sponsors to optimize dose, respond to evolving expectations, and accelerate early‑phase development.

Scaling Pharmacovigilance: Clinical Development To Commercialization

Commercial growth brings new PV challenges. Gain practical insights on operating models, technology, governance, and leadership for long-term success.

Empowering Patients With Self-Administration Drug Delivery Devices

Discover how these devices offer solutions to the challenges of precise dosing, patient compliance, retention, and safety, uplifting the overall trial experience and providing real world insights.

Cross-Functional Best Practices For Signal Detection

When trial data fall short, real risk signals surface in inquiries, complaints, and reports. Learn how coordinated, cross-functional practices help catch risk earlier.

Precision-ERA Medicine, Now In Autoimmune Mode

Mechanism-specific autoimmune treatments demand deeper biological insight. Discover how an integrated trial strategy improves signal detection.

DECENTRALIZED TRIALS

4 Steps To Make A Business Case For Digital Endpoints

Anita Burrell explains how to build a business case for including digital endpoints and the elements to consider.

Hybrid And Decentralized CNS Clinical Trials: Finding The Right Balance

Decentralized and hybrid trial models are reshaping CNS research. Learn how to match virtual tools to your study design, endpoints, and patient population for better outcomes.

Guiding GLP-1 Participants Through The Challenge Of Retention

Learn how remote lifestyle coaching can combat high dropout rates in metabolic research by offering the support participants need to maintain adherence and ensure data integrity.

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