Insights On Trial Design

  1. 4 Potential Advantages Of Adaptive Design
    1/9/2019

    Adaptive design strategies have been especially useful for rare disease research in general and rare oncology in particular. Read more to see how the savvy application of adaptive trial design compares to conventional study designs.

  2. 5 Endpoints For Rare Oncology Trials
    1/9/2019

    For patients battling rare cancers, especially those lacking standard treatments, they don’t have the time to wait for more concrete measures. In these cases, choosing the appropriate endpoint for a trial is crucial. Read on for a rundown of the five major types of clinical endpoints in rare oncology and the best way to use them.

  3. SEO, UX Key To Finding – And Understanding – Clinical Trials
    1/8/2019

    According to experts, sponsors’ clinical trials websites should focus on three primary areas: patient-centric content and design, navigation and mobile friendliness.

  4. Why Clinical Trial Sponsors Should Become More Transparent
    1/8/2019

    Transparency means different things to different segments of the healthcare industry and to consumers themselves. In this blog, a former R.N. and clinical trial participant shares her insights on why clinical trial transparency is so important.

  5. The Complex Issues With Developing A Novel Human Antibody From Scratch
    12/26/2018

    Having the right specialists on their team enables Premier Research to recruit subjects relatively quickly, despite extremely complex selection criteria for this multiple myeloma clinical trial. In addition, maintaining a close and cooperative customer relationship assisted in moving the study forward.

  6. Overcoming The Challenge Of Enrolling Sickle Cell Patients In Clinical Trials
    12/26/2018

    Premier Research was given a tight timeline of less than four months from delivery of the final protocol to first patient in. With proper site selection to accommodate the needs of a fast start-up along with open and frequent communication with the principle investigator and the project team, they were able to meet this timeline.

  7. Recruiting Hard-To-Find Patients From A Specific HLA Subgroup
    12/26/2018

    CRO helps company overcome early patient screening failure rate of 70 percent as well as assisting with instituting new protocols and renegotiating contracts as the study experiences and major change of direction.

  8. Lengthy Cancer Drug Study Using Dozens Of Sites Yields Positive Results
    12/26/2018

    After lengthy recruiting process and a five year long clinical trial spread across more than two dozen sites, sponsor calls study results “an unexpectedly huge step forward” in overcoming the limited efficacy of current treatments and continues partnership with CRO.

  9. Five Things To Know When it Comes To iRECIST
    12/26/2018

    Here are five things you should know about iRECIST as the standard shapes up as an important tool in assessing solid tumors.

  10. Maximizing Success In Early Stage Oncology Trials: Considerations And Strategies In The Era Of Molecularly Targeted Agents
    12/26/2018

    Making a meaningful impact on the survival and quality of life of patients with cancer remains a significant challenge. This white paper discusses considerations and strategies for maximizing the likelihood of success in early phase oncology trials and developing significantly improved therapeutics for patients.