FEATURED ARTICLES

New Patch Technology Will Help Scintilla Treat Pain
New Patch Technology Will Help Scintilla Treat Pain

Pain management company Scintilla Pharmaceuticals has announced it will acquire SCILEX Pharmaceuticals to bolster its pain management business. SCILEX is engaged in the development and commercialization of products focused on the treatment of pain. Its lead product candidate, ZTlido, is a branded lidocaine patch formulation being developed for the treatment of postherpetic neuralgia, the chronic pain that sometimes develops with shingles.

  • Will Cyclobenzaprine Be A Solution For Fibromyalgia Patients?
    Will Cyclobenzaprine Be A Solution For Fibromyalgia Patients?

    Seth Lederman, M.D. has worked with many patients with fibromyalgia as a physician, and knows they have waited long enough for relief from its symptoms. “Those symptoms can quickly take over their lives,” he says. “Fibromyalgia is considered to be a pain disorder but it’s much more than that.”

  • Is There A Link Between The France Tragedy And Legal Highs?
    Is There A Link Between The France Tragedy And Legal Highs?

    By now you have heard about the tragic clinical trial in France that has resulted in the death of one person and the hospitalization of four others. While full details of what caused the fatal death of a healthy man are still not available, we do know the trial was likely testing an FAAH-inhibitor. Maia Szalavitz, writing on the website Vice.com, says this should be a wakeup call to some legal substance users in the U.S.

  • How Do I Get My Compound Into Phase I?
    How Do I Get My Compound Into Phase I?

    The primary challenge for pharmaceutical and biotechnology companies in developing their drugs is to carefully assess the relationship between efficacy and toxicity prior to entering into human clinical trials. By Dr. Scott E. Boley and Greg Ruppert

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WHITE PAPERS & CASE STUDIES

  • Considerations For Development And Approval Of Analgesic Products

    The regulatory landscape for the development and approval of analgesic products has a well-documented history in the literature and the regulatory annals for these extremely important therapeutic compounds. Current products range from the frequently administered non-steroidal anti-inflammatory drugs (NSAIDs) for treatment of acute pain, osteoarthritis and other sensory/nociceptive pain to the controlled opioids, Selective Serotonin Reuptake Inhibitors/Serotonin and Norepinephrine Reuptake Inhibitors (SSRIs/SNRIs), and gamma-Aminobutyric acid (GABA) analogues that relieve pain of a more chronic and neuropathic nature. By David Shoemaker, Senior Vice President, Research and Development, Rho

  • Importance Of Preclinical Imaging In Drug Discovery

    The process of discovering and bringing a drug to market consists of several stages, beginning with identification and validation of a drug target and continuing through lead identification by high-throughput screening, lead optimization, and profiling in relevant disease models.

  • PHT’s LogPad® Direct Clinical Data Collection For Pain Studies

    This paper describes the application of the PHT LogPad® to studies in the therapeutic area of pain. It is intended as a summary educational document for readers familiar with clinical trials.

  • Patient Osteoarthritis Of The Knee Pain Case Study

    ePharmaSolutions, a global study launch and site support services company, developed and deployed a highly effective patient recruitment campaign that yielded an outstanding number of qualified referrals to support an osteoarthritis of the knee study in patients that were currently on a medication regimen.

  • Therapeutic Expertise: Neuroscience & CNS Datasheet PRA is a leader in the clinical research industry, providing innovative solutions for CNS drug development.
  • Point Of Care Lactate Testing Predicts Mortality Of Severe Sepsis In A Predominantly HIV Type 1-Infected Patient Population In Uganda To evaluate the ability of a handheld portable whole-blood lactate (PWBL) analyzer to predict mortality in patients who are admitted to the hospital with severe sepsis.
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