ARTICLES BY ELAINE EISENBEISZ

• Adaptive Seamless Design For Phase 2/3 Studies: Basic Concepts & Considerations

  4/24/2018

  An adaptive design is a design that allows for modifications to the processes and statistical procedures of a clinical trial, usually at set intervals established in the trial protocol. Adaptive designs are useful for increasing efficiency and lowering costs associated with clinical research. Studies incorporating adaptive design techniques can be useful in redirecting subject allocation to concentrate on the most promising treatments or in stopping a trial early for futility. The temporal and monetary savings resulting from adaptive designs make them of great value in drug and medical device development.

• An Introduction To Contingency Tables For Clinical Study Analysis

  1/2/2018

  I would guess every researcher has come across a contingency table. Contingency tables are a type of classification table used in statistics to simultaneously summarize relationships between two categorical variables. (Let’s call them Variable X and Variable Y.) Contingency tables are also called two-way tables, cross-tabulation tables (cross-tabs), and frequency distribution tables, because statisticians like to have at least three to five names for everything.

• 5 (Fairly Simple) Statistical Analysis Plan Elements To Implement In Your Clinical Study

  11/28/2017

  My father used to say, “If you are going to do something half-assed, don’t do it at all.”