Site Management/Investigator Payments Featured Articles

1. What Clinical Operations Should Know About Medical Affairs And MSLs 8/20/2025

   Having spent years in medical affairs and leading MSL teams, William Soliman, Ph.D., BCMAS, explores how clinical operations and medical affairs thrive in collaboration or struggle in silos and offers tips for better partnerships.

2. AI-Enhanced Clinical Project Management For Cell And Gene Therapy Clinical Trials 8/12/2025

   Consultant Jessica Cordes explores two of the most critical uses of AI for cell and gene therapy clinical trials: real-time patient journey coordination and predictive enrollment. 

3. Running Global Clinical Trials? PolyPid Shares Operational And Regulatory Insights 8/11/2025

   PolyPid shares its clinical trial journey across the U.S., Europe, and Israel, highlighting operational complexities, regulatory navigation, and the adaptability required to execute large-scale, global studies. 

4. Why CRO Site Network Strategies Confuse Me 8/6/2025

   As CROs evolve beyond traditional service roles, many are investing in proprietary or semi-integrated site networks to streamline trial delivery, improve patient access, and boost data consistency. This article explores how major players like ICON, Parexel, PPD, and Syneos Health are building or partnering with site networks—sometimes through direct ownership, sometimes through curated alliances.

5. When Survival Comes First, Trials Come Last 8/1/2025

   Infectious disease PI Dr. Claudia Martorell has long focused on recruiting underserved populations into clinical trials. But amid healthcare cuts, economic instability, and a retreat from DEI initiatives, she’s now watching access unravel. In this interview, Martorell shares what happens when survival takes priority over research — and why diversity in trials is once again at risk.

6. Paving The Way For Sites To Use Their Own Tech 7/17/2025

   The DTRA has released a detailed playbook to help clinical research sites use their own validated technology in sponsor-led trials. The "Bring Your Own Technology" (BYOT) model aims to reduce tech overload at sites, improve efficiency, and preserve regulatory compliance — starting with eConsent as its first use case.

7. How An Australia-First Strategy Cut 63% From Our R&D Spend 7/10/2025

   Etira CEO Russell Hayward explains how conducting the company's early-stage trials in Australia has yielded big savings, shortened timelines, and produced FDA-ready data.

8. Imunon Talks Passionate PIs, Endpoint Selection In Frontline Ovarian Cancer Trials 7/9/2025

   IMUNON CEO Stacy Lindborg, Ph.D. details the company’s successes in site selection, as well as trial design and execution, in Phase 2 and 3 trials for IMNN-001, a frontline treatment for ovarian cancer.

9. PI's CRAACO Model + AI = Rapid Enrollment 6/30/2025

   At Dr. David Almeida’s clinical trial site in Erie, PA, he practices the CRAACO model exclusively, relying on the revenue he makes from conducting clinical trials for eye-related diseases. To minimize his costs and speed up trial enrollment, he uses a proprietary AI system that has given him an 85% screen-to-enroll ratio.

10. It's Time To Change How We Engage Research Sites 6/25/2025

    Site operations expert Maria Ladd argues for a major change in how sponsors and CROs communicate and work with clinical research sites.