FEATURED ARTICLES
ALS Researchers Use Stratification, Diverse Endpoints To Address Heterogeneity
Coya Therapeutics' Fred Grossman dives into innovative trial design elements and a novel biomarker that might better account for clinical and functional progression in Coya's ALS trial studying a dual immunomodulatory therapy.
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Justice In Human Participant Research: Reinterpreting Belmont For Contemporary Clinical Trials
Experienced IRB professional Stephanie Pyle revisits the Belmont Report to consider what its principle of “justice” means for research studies developed and conducted today.
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Philanthropy Empowers And Accelerates Testing Of Drug Combinations In T1D
City of Hope’s Alberto Pugliese, MD, discusses how philanthropic gifts helped launch a landmark multi-center trial to test a combination therapy using repurposed drugs for the treatment of Type 1 Diabetes.
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The Patient-Centered Trial Paradigm For Knee Osteoarthritis
Although PROs can complicate a trial design, they're essential to reflecting a patient’s true knee OA experience and producing meaningful evidence, explains Katie Mowry, Ph.D., VP of R&D at Organogensis.