Greenphire is the leader in global clinical trial payment automation. Greenphire’s best-in-class solutions optimize clinical trial performance by streamlining payment workflows from sponsors and CROs to sites and participants. Greenphire’s ClinCard, eClinicalGPS and ConneX solutions easily handle any type of trial design and complexity, resulting in more accurate and compliant payments and travel globally for both sites and participants. The choice of industry leaders worldwide, Greenphire provides better performance and better data, resulting in better trials. Learn more at www.greenphire.com.


Greenphire's EnvisiX solution is a budget build and negotiation tool that enables sponsors and CROs to effectively and efficiently build a study budget. The tool provides a streamlined and controlled workflow for budget negotiation for sponsors and CROs with complete transparency and management of rates, adjustments, adjudications, approvals and more.

ConneX is a global travel solution providing in-market services and support, designed to meet the unique travel needs of each study, whether it be for rare disease, diverse populations, pediatrics, etc. Our offering removes the burden of complex travel arrangement from site staff, while peace of mind is established for participants, their families and caregivers.

With more than 7 million payments, ClinCard is the industry-leading method for automated participant payments, delivering unmatched simplicity, security, and global reach.

eClinicalGPS is designed to automate and streamline clinical site payments, getting sites paid faster and more accurately with less administrative burden. Configured


Today’s clinical trials are more complicated and demanding than ever before. They’re often global, costly and require cumbersome travel. Greenphire is changing that. With our solutions, you can manage the entire financial lifecycle for trials conducted all over the world. Greenphire works directly with leading research institutions, sites, sponsors and CROs to simplify clinical trials and facilitate stronger, more collaborative relationships. With solutions that streamline your workflows, you can focus on providing better patient care.   

The site budgeting and contracting process is critical to the success of a clinical trial. Enhance your study design and startup with EnvisiX. Watch this short video to learn more.

ConneX interview with Jim and Kyle - Part 7 Jim summarizes the end goal of Greenphire's ConneX Expert Travel Solution - focusing on making the clinical trial experience as simple as possible for participants while reducing the administrative burdens on the site.

ConneX interview with Jim and Kyle - Part 4 Kyle talks about the importance of patient convenience (humanizing clinical research) - removing the barrier of participation in clinical trials.

Director of Clinical Research at MidLantic Urology, Cheryl Zinar, discusses how introducing rideshare has improved the clinical trial experience for all stakeholders – Added convenience and removed out-of-pocket costs for patients, simple workflow and improved control for study coordinators and increased enrollment and reduced costs for the site.

ConneX is the most comprehensive clinical trial travel solution designed to meet the unique needs of your global trials.  

Sponsors, CROs and sites around the world partner with Greenphire to enable a secure and compliant electronic payment technology that makes their lives easier and removes the barriers to successful recruitment and retention. Watch this video to see how it works!

Learn how Greenphire's eClinicalGPS site payment solution offers flexible delivery models to maximize ROI, adoption, and help sponsors and CROs meet their business objectives.

Learn how automating payments to research sites improves research site performance, supports site sustainability and delivers a more collaborative, trusting relationship between research stakeholders.

Gain an understanding around site payment burdens and how our solutions can empower sites around the world.

Learn the advantages that sponsors and CROs gain when choosing to automate site grant payments.



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  • The COVID-19 pandemic added new obstacles and complexity on top of the already difficult environment, creating enormous adaptive pressure on the entire clinical trial ecosystem, hastening adoption of new clinical research paradigms, and accelerating emerging trends. But will they sustain? In this paper, we will delve into hot topics impacting research today.

  • According to a recent ACSCAN report, out of all potential qualifying patients for a trial, only 44% of them have access to an available trial, only 27% are eligible for the trial, and only 8% are able to successfully enroll in a study. These are just the barriers leading up to trial participation. Once a patient is enrolled, there are many obstacles that can impact patient retention in a study. Let’s discuss some of the obstacles facing oncology research today and highlight innovation opportunities to transform the way sites, sponsors, and CROs interact.

  • In 2020 the clinical trial industry adapted and responded in rapid fashion. Measures were taken to allow for continuity of studies, all while shortening timelines and ensuring safety and flexibility of care. This flexibility can be seen through trial decentralization – enabling care to be continued through varying methods, whether bringing care to the patient’s home, allowing patients to benefit from local labs or utilizing technology to complete trial requirements. This response by the industry was impressive and perhaps provides a glimpse into the future of clinical research. But what does the future look like?

  • The underrepresentation of certain populations in clinical research is a serious problem. However, sponsors and CROs are renewing their focus on diversity, and are looking for new ways to create awareness and remove obstacles through patient-centered solutions.

  • With COVID-19 dominating the headlines, many study sponsors and CROs have turned to us to help with initiating patient and site-centric technology solutions for their clinical trials in 2020. In this short blog, we share with you some of the insights we’ve gleaned from working with top sponsors, CROs and sites on COVID-19 and other vaccine studies. These may be helpful as you plan for 2021.

  • Greenphire, the global leader in financial lifecycle management for clinical trials, says patient enrollment for global clinical trials has returned to pre-COVID levels. Research spotlights the need for technological solutions to help participants suffering through financial and logistical hardships to stay enrolled in studies.

  • With the current clinical trial logistical challenges there comes the need for ingenuity – partnering with a travel provider who can navigate these difficult and uncertain times to ensure sustainability for the trial.

  • This paper seeks to explore the most crucial obstacles to successful budget design and negotiation in light of the current complexity experienced across the clinical trial universe. It highlights how technology can streamline these traditionally manual, time-consuming workflows, increase transparency and predictability, and deliver more current, and accurate data for an optimized study start-up.

  • In 2010, MJFF launched a large-scale clinical study conducted at a network of clinical sites around the world focused on identifying and validating Parkinson’s disease biomarkers. The study realized it needed a new way to ensure that participants were remaining engaged throughout the long protocol and that the experience was as seamless as possible for both the volunteers and the site coordinators. They were able to source a solution to support patient-centricity, as well as study site efficiency.

  • This guide focuses on important areas to evaluate when vetting a platform for clinical research participant reimbursement. These crucial elements will help ensure the system you select improves the participant experience without increasing the burden on site staff.

  • In partnership with the Society for Clinical Research Sites, Greenphire has conducted a survey to hear directly from sites regarding Investigator Grant Payments. As such, we would like to share insights from the survey and suggestions for improving site satisfaction as it relates to invoicing and payment processes. Here is a list of 10 things sites say sponsors and/or CROs do that add stress to the relationship.

  • COVID-19 has had a dramatic impact on US clinical care, including how sites have worked to maintain research operations throughout the pandemic. The financial and logistical challenges faced by our site partners have been substantial, here is a recap of the adaptations they’ve made to manage through the current environment.

  • Protocol complexities are becoming ever more complex, and with it, so has the clinical trial budgeting process. Plagued by multiple stakeholders using disconnected systems across the globe, delays and increased costs in study start up follow. Discover what sponsors need to consider in order to achieve first patient in as swiftly as possible.

  • There are challenges associated with conducting clinical trials in newer markets. Processes and regulations may differ by country/region, making standardization across a global study nearly impossible. The key to developing solutions that meet all clinical and administrative workflow requirements and regulations is to listen to those who live and breathe these processes.

  • Recently, both the FDA and EMA issued guidance with regards to the conduct of clinical trials during the COVID-19 pandemic. These latest regulatory guidelines permit sites, sponsors and CROs to adjust their study operations to meet changing conditions for ongoing trials, however there are conditions that must be met in order for new solutions to be considered. Here are six steps the industry can take to support the needs of patients and sites.

  • Many times sponsors go with a site payment solution they thought would work - only to find out the "automation" is not so automatic - that customer support is outsourced, spreadsheets still need to be emailed back and forth and sites are still calling asking questions. Following is a list of things to consider when choosing to implement investigator payment technology to avoid this situation.

  • In this paper, we dive into the logistical and financial challenges which increasingly impact all clinical trial stakeholders - from patients and sites, to sponsors and contract research organizations (CROs). Yet with proper planning and the right partners on board, travel arrangements and reimbursement programs can make the trial and patient experience more comfortable and successful for everyone.

  • The new age transportation method, Rideshare, is growing in popularity amongst everyday travelers, but has also been found to provide significant advantages for clinical trials. This blog outlines ten Benefits of utilizing Rideshare through an expert provider in clinical workflow optimization.

  • Whether your trial isn’t starting for six months or has already started, assessing new solutions and adopting best practices through automation can streamline your operations and improve patient retention.

  • Midlantic Urology Associates had been employing a single driver for all participant pick-ups. This proved to be inefficient and unsustainable, so they began utilizing taxis. This alternative was costly and unreliable – there had to be a better way. ClinCard’s integration with Lyft has not only improved the experience for patients and study coordinators but has also helped with recruitment as new patients are enrolling in the study as a result of this added convenience.